|AIDS patients have an increased susceptibility to develop multiple malignant neoplasms. The association between leiomyosarcoma and EBV in AIDS is widely recognized. The sarcoma commonly occurs in gastrointestinal tract, uterus and lungs. Less commonly, it can also involve liver, spleen, adrenal gland, lesser sphenoidal wing, cavernous sinus, and orbit. Iris leiomyosarcoma is an extremely rare malignant tumor. It arises from the dilator and sphincter muscles, which are of neuroectoderm in origin. Dilated ophthalmoscopy revealed inactive CMV retinitis confined in the posterior pole OU. Gonioscopy showed a tumor occupying the inferior peripheral iris adjacent to the anterior chamber angle, which remained open. A blood reflux into the nearby schlemmâs canal was observed. Initial ultrasound biomicroscopy (UBM) revealed a hypoechoic oval mass extending from the pupil.
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