Pancytopenia

Reactive bone marrow plasmacytosis occurs in association with a variety of conditions, such as chronic infections, autoimmune diseases, connective tissue and chronic granulomatous disorders, diabetes mellitus, hypersensitivity states, drug-related agranulocytosis, iron deficiency, megaloblastic and hemolytic anemia, hemopoietic and non-hemopoietic malignant diseases, angio-immunoblastic lymphadenopathy, and multicentric Castleman’s disease .In such reactive cases, Plasma Cells (PCs) usually account for 10%-20% of cells in bone marrow trephine biopsy sections and rarely exceed 50%. Chest X-ray and thorax Computed Tomography (CT) showed evidence of pneumonic infiltrate in the left lower lobe. After blood, urine, and sputum cultures were obtained, the patient was treated with imipenem 5 μg/kg/day for febrile neutropenia and Granulocyte Colony-Stimulating Factor (G-CSF). Bone marrow aplasia associated with prominent atypical plasma cell proliferation (96% of all nucleated cells exhibited transient pancytopenia) and hypoplastic bone marrow. Zafer Gokgoz, Prominent Reactive Plasmacytic Proliferation Presenting with Transient Pancytopenia: An Unusual Case The top open access journals are peer reviewed scholarly journals of Hematology & Thromboembolic DiseasesThe top open access journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community. These journals are indexed with all their citations noted. The top open access journals are indexed in MEDLINE, PUBMED, SCOPUS, COPERNICUS, CAS, EBSCO and ISI.

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Last date updated on April, 2024