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Cancer chemoprevention involves the chronic administration of a synthetic, natural or biological agent to reduce or delay the occurrence of malignant tumour. The potential value of this approach has been demonstrated with trials in breast, prostate and colon cancer. The paradigm for developing new chemo preventive agents has changed markedly in the last decade and now involves extensive preclinical mechanistic evaluation of agents before clinical trials are instituted and a focus on defining biomarkers of activity that can be used as early predictors of efficacy.
Chemoprevention related journals
Advances in Gastrointestinal Cancers, Journal of Gastric Cancer, Academic Journal of Cancer Research, Advances in Breast Cancer, European Journal of Cancer.