As early as 22 July 1942 there was an initial amendment the CSIC’s founding law which introduced some changes, all designed to improve its operational structure. Changes were made to the various governing bodies, including in particular the grouping of the boards into three sections (Humanities and Social Sciences, Science and Technology, and Biology and Natural Resources), each headed by a vice president. Both the structure of the sections and the thematic vice presidencies were maintained over the following four decades. The position of technical research director was also created. In 1958 one of the responsibilities assigned to the CSIC in the founding law (“to promote, guide and coordinate scientific research”) was transferred with the creation of the Advisory Committee on Scientific and Technical Research. In order to make a clear differentiation, it was exhaustively stated that the new Authority may not establish its own centres. The CSIC comprises a network of centres and institutes distributed throughout the country, including joint centres run in conjunction with universities, regional governments and other organisations. It is present in all Spain’s Autonomous Communities, and also has a centre in Italy: the Escuela Española de Historia y Arqueología in Rome. The CSIC’s centres and institutes are independently managed and have their own scientific research agenda. All the CSIC’s centres are headed by a director and are subdivided into departments which host research groups working on related topics. Thus, while the CSIC’s research groups are the operational units when it comes to conducting research, for administrative and organisational purposes the CSIC is subdivided into centres and institutes. The CSIC’s centres and institutes are classed in eight major scientific and technical areas based on the type of the research they perform. In some cases the lines of research carried out in a given centre or institute are such that it is assigned to more than one scientific or technical area. As well as the CSICs institutes, it also has research units and approximately 160 associate units that have been set up by groups or departments at universities, hospitals and technology centres that are working on research projects or lines in close collaboration with the CSIC. There are in 10,547 staffs in total working under CSIC. In 2015 CSIC have signed more than 2,796 contracts. The financial management body have decided the budget of 684.9 euros annually. And the income budget which was achieved was 691.6 million euros and the expenditure was calculated as 669 million euros annually. There are almost 311, 7 projects are in action which accounts for 507.2 million euros. The CSIC Action Plan 2010-2013 promotes transdisciplinary research focused on complex issues, which will undoubtedly benefit from the multidisciplinarity of the CSIC. This strategic line of focused research is called Focus. This line is intended to promote transdisciplinary, focused research, oriented to problems and needs whose resolution would benefit from approaches with multiple optics. Focus contemplates the enhancement of research in five defined themes: the Strategic Focus Axes. The research done by the CSIC state agency is arranged around eight major scientific-technical areas that cover most of human knowledge, from the most basic or fundamental aspects of science to the most complex technological developments; from human and social sciences to food science and technology, including biology, biomedicine, physics, chemistry and materials, natural resources and agricultural sciences. The eight areas of knowledge are: Humanities and Social Sciences, Biology and Biomedicine, Natural Resources, Agricultural Sciences, Physical Science and Technologies, Materials Science and Technology, Food Science and Technology, Chemical Science and Technology.