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Nebraska Center for Virology University of Nebraska-Lincoln

It was established under the NIH Institutional Development Award program. Combines the expertise of Nebraska’s leading biomedical research institutions: University of Nebraska-Lincoln and University of Nebraska Medical Center. It focuses on viral diseases of humans, including HIV-1, Kaposi’s Sarcoma and herpes.It is supported by Flow Cytometry and Bioinformatics.
Current research activities are carried out on herpesvirinae subfamily members. Study is often carried out on two a-herpesvirinae subfamily members, Bovine Herpes Virus Type 1 (BHV-1) and Herpes Simplex Virus Type 1 (HSV-1), to identify common signaling pathways that regulate the latency-reactivation cycle. As BHV-1 causes respiratory disease, abortion, occasionally encephalitis, and is a causative agent of Bovine Respiratory Complex it is a significant viral pathogen of cattle HSV-1 causes corneal blindness and encephalitis, and 25% of all new genital herpes cases. BHV-1 and HSV-1 are important pathogens of their respective hosts.
The Nebraska Center for Virology research topics are challenging and meritorious exploring problems of epidemic proportions facing mankind including AIDS and HIV replication and pathogenesis, herpesvirus latency and cancer, human papilloma virus and cancers, and chlorellavirus biology. Our goals include designing novel vaccines and therapeutic strategies to block disease.

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