Alcoholism

As per available reports about 327 journals, 10 Conferences, 503 workshops are presently dedicated exclusively to Alcoholism Disease and about 395,000 articles are being published on the current trends in Alcoholism. In terms of research annually, USA, India, Japan, Brazil and Canada are some of the leading countries where maximum studies related to proteomics are being carried out. As reported in Wikipedia, Alcoholism is a term that encompasses the hepatic manifestations of alcohol overconsumption, including fatty liver, alcoholic hepatitis, and chronic hepatitis with hepatic fibrosis or cirrhosis.
It is the major cause of liver disease in Western countries. Although steatosis (fatty liver) will develop in any individual who consumes a large quantity of alcoholic beverages over a long period of time, this process is transient and reversible. Of all chronic heavy drinkers, only 15–20% develop hepatitis or cirrhosis, which can occur concomitantly or in succession.
How alcohol damages the liver is not completely understood. 80% of alcohol passes through the liver to be detoxified. Chronic consumption of alcohol results in the secretion of pro-inflammatory cytokines (TNF-alpha, Interleukin 6 [IL6] and Interleukin 8 [IL8]), oxidative stress, lipid peroxidation, and acetaldehyde toxicity. These factors cause inflammation, apoptosis and eventually fibrosis of liver cells. Why this occurs in only a few individuals is still unclear. Additionally, the liver has tremendous capacity to regenerate and even when 75% of hepatocytes are dead, it continues to function as normal.
The Journal of Alcoholism & Drug Dependence is an academic journal – hosted by OMICS International – a pioneer in open access publishing–and is listed among the top 10 journals in Alcoholism Disease. Each year research scientists have noticed a rise in the number of congresses being held in this field. The Journal of Alcoholism & Drug Dependence provides a unique platform to researchers and scientist to explore the advanced and latest research developments in the field of Alcoholism & Drug Dependence, thus bridging the gap between researchers and young scientists.