DNA sequences

The procedure of determining the order of base pairs in section of DNA. the DNA code is made up of four different bases: A, T, C, and G. And so the question is 'when you have a different gene, what are the sequence of those bases?', and so you go through and actually identify whether its an A, a T, a C, or a G and you do that for the entire genome and then you have a genome sequence. So you can actually know the genetic makeup of an entire organism just by knowing those four bases, the order they occur in, and where they occur on a chromosome.

As per available reports about 110 journals, 63 Conferences, 11 workshops are presently dedicated exclusively to DNA sequences and about  3,040,000 articles are being published on the current trends in DNA sequences. In terms of research annually, USA, India, Japan, Brazil and Canada are some of the leading countries where maximum studies related to DNA sequences are being carried out.
As reported in Scitable by nature education article DNA sequencing is a laboratory method used to determine the sequence of a DNA molecule. The method was developed by Frederick Sanger in 1975, who was later awarded the Nobel Prize in chemistry in 1980 for his contributions to understanding DNA sequences. Consequently, it is often referred to as Sanger Sequencing.
In Sanger sequencing, the DNA to be sequenced serves as a template for DNA synthesis. A DNA primer is designed to be a starting point for DNA synthesis on the strand of DNA to be sequenced. Four individual DNA synthesis reactions are performed. The four reactions include normal A, G, C, and T deoxynucleotide triphosphates (dNTPs), and each contains a low level of one of four dideoxynucleotide triphosphates (ddNTPs): ddATP, ddGTP, ddCTP, or ddTTP. The four reactions can be named A, G, C and T, according to which of the four ddNTPs was included. When a ddNTP is incorporated into a chain of nucleotides, synthesis terminates. This is because the ddNTP molecule lacks a 3' hydroxyl group, which is required to form a link with the next nucleotide in the chain. Since the ddNTPs are randomly incorporated, synthesis terminates at many different positions for each reaction.
Following synthesis, the products of the A, G, C, and T reactions are individually loaded into four lanes of a single gel and separated using gel electrophoresis, a method that separates DNA fragments by their sizes. The bands of the gel are detected, and then the sequence is read from the bottom of the gel to the top, including bands in all four lanes. For instance, if the lowest band across all four lanes appears in the A reaction lane, then the first nucleotide in the sequence is A. Then if the next band from bottom to top appears in the T lane, the second nucleotide in the sequence is T, and so on. Due to the use of dideoxynucleotides in the reactions, Sanger sequencing is also called "dideoxy" sequencing.
The Journal of Clinical & Cellular Immunology is an academic journal – hosted by OMICS International – a pioneer in open access publishing–and is listed among the top 10 journals in DNA sequences. Each year research scientists have noticed a rise in the number of congresses being held in this field. The Journal of Clinical & Cellular Immunology provides a unique platform to researchers and scientist to explore the advanced and latest research developments in the field of DNA sequences and bioinformatics, thus bridging the gap between researchers and young scientists.
OMICS International – a pioneer in organizing international conferences is organizing 3rd international conference on clinical and cellular immunology (Immunology Summit -2014) September 29-october 01,2014,Baltimore,USA
OMICS Group hosts over 400 leading-edge peer reviewed Open Access Journals and organize over 300 International Conferences annually all over the world. OMICS International journals have over 3 million readers and the fame and success of the same can be attributed to the strong editorial board which contains over 30000 eminent personalities that ensure a rapid, quality and quick review process. OMICS Group signed an agreement with more than 500 International Societies to make healthcare information Open Access.