Reactive bone marrow plasmacytosis occurs in association with a variety of conditions, such as chronic infections, autoimmune diseases, connective tissue and chronic granulomatous disorders, diabetes mellitus, hypersensitivity states, drug-related agranulocytosis,
iron deficiency, megaloblastic and hemolytic anemia, hemopoietic and non-hemopoietic malignant diseases, angio-immunoblastic lymphadenopathy, and multicentric Castlemanâs disease .In such reactive cases, Plasma Cells (PCs) usually account for 10%-20% of cells
in bone marrow trephine biopsy sections and rarely exceed 50%. Chest X-ray and thorax Computed Tomography (CT) showed evidence of pneumonic infiltrate in the left lower lobe. After blood, urine, and sputum cultures were obtained, the patient was treated with imipenem 5 Î¼g/kg/day for febrile neutropenia and Granulocyte Colony-Stimulating Factor (G-CSF). Bone marrow aplasia associated with prominent atypical plasma cell proliferation (96% of all nucleated cells exhibited transient pancytopenia) and hypoplastic bone marrow.
Zafer Gokgoz, Prominent Reactive Plasmacytic Proliferation Presenting with Transient
Pancytopenia: An Unusual Case
The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.
Last date updated on September, 2014