Reactive bone marrow plasmacytosis occurs in association with a variety of conditions, such as chronic infections, autoimmune diseases, connective tissue and chronic granulomatous disorders, diabetes mellitus, hypersensitivity states, drug-related agranulocytosis,
iron deficiency, megaloblastic and hemolytic anemia, hemopoietic and non-hemopoietic malignant diseases, angio-immunoblastic lymphadenopathy, and multicentric Castlemanâs disease .In such reactive cases, Plasma Cells (PCs) usually account for 10%-20% of cells
in bone marrow trephine biopsy sections and rarely exceed 50%. Chest X-ray and thorax Computed Tomography (CT) showed evidence of pneumonic infiltrate in the left lower lobe. After blood, urine, and sputum cultures were obtained, the patient was treated with imipenem 5 Î¼g/kg/day for febrile neutropenia and Granulocyte Colony-Stimulating Factor (G-CSF). Bone marrow aplasia associated with prominent atypical plasma cell proliferation (96% of all nucleated cells exhibited transient pancytopenia) and hypoplastic bone marrow.
Zafer Gokgoz, Prominent Reactive Plasmacytic Proliferation Presenting with Transient
Pancytopenia: An Unusual Case
A journal is a periodical publication intended to further progress of science, usually by reporting new research. Most journals are highly specialized, although some of the oldest journals publish articles, reviews, editorials, short communications, letters, and scientific papers across a wide range of scientific fields. Journals contain articles that peer reviewed, in an attempt to ensure that articles meet the journal's standards of quality, and scientific validity. Each such journal article becomes part of the permanent scientific record.
Last date updated on September, 2014