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Benaroya Research Institute (BRI, formally called Benaroya Research Institute at Virginia Mason) is a Seattle, Washington non-profit organization that conducts autoimmune disease medical research. It is affiliated with Virginia Mason Health System and located on the campus of Virginia Mason Medical Center. Much of BRI’s research aims to uncover how immune cells function and why they malfunction to cause disease. BRI uses translational research and clinical trials to carry its discoveries from the lab to the clinic, improving how physicians diagnose and treat disease.