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The Jenner Institute was founded in November 2005 to develop innovative vaccines against major global diseases. Uniquely it focuses both on diseases of humans and livestock and tests new vaccine approaches in parallel in different species. A major theme is translational research involving the rapid early-stage development and assessment of new vaccines in clinical trials. The Institute comprises the research activities of over 30 Jenner Investigators who head leading research groups spanning human and veterinary vaccine research and development. Together the Institute Investigators comprise one of the largest non-profit sector research and development activities in vaccinology. Jenner Institute Investigators, through the support of many funders, are developing new vaccine candidates against major global infectious diseases. New vaccines against malaria, tuberculosis and HIV are currently in field trials in the developing world. Research is also underway on livestock vaccines against foot and mouth disease, avian influenza, bovine tuberculosis and other major causes of economic loss.
Research Programmes:The Institutes research activities are grouped into 14 vaccine programmes (listed right), covering a wide range of human and veterinary diseases. Each programme is headed by one or several Jenner Investigators. The Investigators are independent researchers located at different sites of the University of Oxford or the The Pirbright Institute. Two Jenner Investigators are also located at the Animal and Plant Health Agency. Administration and facilitation of collaborations between Jenner Investigators and researchers is undertaken at the Jenner Institute Laboratories, where the Institutes Core Facilities are also located.
People:The Jenner Institute comprises the research activities of 28 Jenner Investigators located at different sites of the University of Oxford, The Pirbright Institute and the Animal Health and Veterinary Laboratories Agency. The administrative headquarters and main laboratories for human vaccine development are located at the Jenner Institute Laboratories, Old Road Campus Research Building, in Headington, Oxford. This model results in an Institute dispersed across multiple sites, providing Investigators with access to a wide range of expertise and specialist Core Facilities. Each Jenner Investigator leads a Vaccine Programme employing post-docs, research assistants and doctoral students to undertake research in one or several disease areas. Programmes in the later stages of vaccine development also include Clinical Research Fellows, who are the trial physicians responsible for the planning, implementation and analysis of clinical vaccine trials in the UK and in overseas field sites.
Core Facilities:Four of the Institutes Core Facilities were established in 2008 with funding from a Wellcome Trust Strategic Award. The purpose of the facilities is to improve and accelerate access to: - key vaccine components, eg. adjuvants and vectors - core technical expertise and equipment - new vaccine candidates to be tested in small scale clinical trials
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