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The Heinrich Pette Institute, Leibniz Institute for Experimental Virology (HPI) was founded in 1948 by Heinrich Pette. It began as a research facility to create a polio vaccine. It is now a private foundation and involved with basic research in virology and the immune responses of organisms. The institute is a non-profit public beneficiary organisation and an independent member of the Leibniz Association, and is located at the University of Hamburg. After his death the Institute was renamed Heinrich Pette Institute for Experimental Virology and Immunology. Since 1993 a cooperation agreement between the HPI and the University of Hamburg underlines the close relation to the university. The Institutes buildings were renovated and extended in 1967, 1995 and in 2006.
The aim of the research at the Heinrich Pette Institute is to develop new approaches for improved diagnostic techniques and therapies for viral diseases and virus-associated tumor diseases. Scholars of the HPI explore a wide range of viruses, such as hepatitis viruses, herpes viruses, leukemia viruses, human immunodeficiency virus and tumor viruses. The drive towards practical applications of the results in diagnosis and treatment is reflected in numerous collaborations with clinical institutions and industry.
The research center for pediatric hematology and oncology Forschungsinstitut Kinderkrebs-Zentrum Hamburg has a part of the HPIs buildings. Based on the Public-Private Partnership the Society operates for the promotion of the replacement and expansion II of the Heinrich Pette Institute, Leibniz Institute for Experimental Virology and is an independent research institute for pediatric hematology and oncology.
In cooperation with the Max Planck Institute for Molecular Cell Biology and Genetics in Dresden, scientists proved that it is possible, using a customized enzyme (Tre recombinase), to excise the DNA of the HIV from the genome of individual cells to remove it. This demonstration is an important step in the development of a cure for AIDS (hence the extensive removal or containment of HIV infection).
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