The National Bureau of Fish Genetic Resources (NBFGR) was established in 1983 and has emerged as a Center of Excellence in cataloguing and conserving the aquatic bioresources of India. The Bureau has developed modern facilities, multidimensional strategies and technological capabilities to achieve its mandate related to database development, genotyping, registration of aquatic germplasm, genebanking and evaluation of endangered and exotic fish species. NBFGR is an ISO 9001: 2008 certified organization and has been awarded with the Sardar Patel Best Institute Award for the year 2011 by the ICAR, New Delhi. The Institute has also established âGanga Aquariumâ, one of the largest and magnificent public aquariums in the country which is serving as a great source of spreading public awareness and education about fish diversity of the country. National Bureau of Fish Genetic Resources has three main divisions. They are molecular biology & biotechnology division for Assessment, characterization and documentation of fish genomic resources, fish conservation division for the development of tools, resources and information on aquatic genetic material for conservation research and applications and fish health management division for accessing the risks and impacts of exotic fish species and to develop strategies and techniques for diagnosis, control and prevention of infectious aquatic animal diseases. Plenty of resources and facilities are available in the divisions like High performance computing (HPC) system with CLC Bio and Discovery Studio software, ABI sequencer 3500, RT-PCR, 2D-Electrophoresis system and Comet image analysis system, Capillary Electrophoresis system, etc. National Bureau of Fish Genetic Resources has developed a non-invasive technique for rapid extraction of DNA from fish scales, generated DNA barcodes over 500 Indian fish species, Generated chromosome profiles of over 70 fish species, explored river basins viz., Indus, Ganga, Ghagghar, Brahmaputra, Mahanadi, Krishna, Godavari and their tributaries to collect the fish accessions for taxonomic validation, stock identification and repository. Lot of funded projects were under this National Bureau of Fish Genetic Resources. NBFGR Library and Documentation Unit acts as a repository of literature and information and provides latest information in the field of fish diversity conservation, fish genetics, fisheries and related aspects. The library added a total of 439 documents comprising 216 books, 164 serials and 59 annual reports. The NBFGR Library is operating in fully automated environment. The various activities of library have been computerized using integrated library management software Libsys. NBFGR maintains the online data bases for different genomes of different kinds of fishes. Lot of events and training programs were conducted for the development of fish bioinformatics grid for the country, Creation of local databases and central data warehouse for genomic resources across species, Analysis and research activities using valuables resources of selected fishes, etc. The Institute has emerged as a Centre of Excellence for research on fish genetic resource management and has made significant contributions in its mandated research areas, as Developed database on fish diversity of India containing information about 2953 finfish species, Developed database on Freshwater Fishes of Northeast and Western Ghats, and fish diversity checklists for eight states and three ecosystems, Developed cell lines from 16 commercially important food and ornamental fish species, which will have application in disease diagnosis. Also developed macrophage cell lines from catla and rohu which can be used as in vitro models for evaluation of immunomodulators and Contributed to the preparation of several policy documents for conservation and sustainable utilization of fish genetic resources, in collaboration with other institutes/agencies, viz., Guidelines for Germplasm Exchange; National Strategic Plan on Aquatic Exotics and Quarantine; National Exotics and Quarantine Guidelines; Guidelines for Green Certification for Freshwater Ornamental Fishes and Model guidelines for Fish and Shellfish Seed Certification in India.