The National Institute for Research in Reproductive Health is dedicated towards addressing the various issues of reproductive health in accordance with the national needs and priorities. We have recently taken several new initiatives in this direction. Sincere attempts are being made to identify genetic and physiological determinants predisposing individuals to testicular, ovarian and endometrial pathologies associated with infertility. We are focusing on the discovery of efficacious targets of anti-HIV therapy, development of new indigenous, efficacious and safe microbicides against HIV/STIs/RTIs. The recently established National Centre for Preclinical Reproductive and Genetic Toxicology will pave the way for discovery of safe and potent drugs. Institute is also striving to derive and characterize embryonic stem cell lines from human and non-human primates. These cell lines will be a great resource for therapeutic applications. Institute has excellent state-of-art facilities for research involving microarrays, proteomics, bioinformatics, nucleic acid sequencing, flow cytometry, electron microscopy, and confocal microscopy. Institute is one of the few centers in India , which can boast of a team of basic, clinical and operational research scientists working towards maximizing the benefits of research outcomes for public health. Our clinical team actively participates in clinical trials for assessment of safety, efficacy and acceptability of various contraceptive methods and microbicides. Institute is actively involved in development of clinical, operational guidelines and information, education and communication material on priority areas for use in the national programs for reproductive health.