In 1921, an anatomopathology specialist, Professor Gustave Roussy, created the first consultation dedicated to patients with cancer in the service of Jean LHermitte at the Paul-Brousse Hospital in Villejuif. In the year of 1925, the General Council of the Seine created the "Regional Center for the fight against cancer in the suburbs of Paris". Led by Professor Gustave Roussy, the center settled next to the Paul-Brousse Hospital and remained there until 1980. The Institut du Cancer was recognized as a public utility in 1927 and became Institut Gustave-Roussy after Death of its founder in 1950. Gustave Roussy is one of the world’s leading cancer-research institutes and the premier European Cancer Centre. The Institute is continuing to invest in the provision of modern and adapted equipment for its patients and care and research teams: research pavilions, laboratory shelf and consulting platform (2005) Building of molecular medicine (2013) It is a centre for patient care, research and teaching. The School of Cancer Sciences was founded jointly by Gustave Roussy and the Faculty of Medicine Paris-Sud. It is a professional training establishment which is unique in France. The members of the teaching body of this multidisciplinary school are practicing physicians and scientists in the leading Comprehensive Cancer Centre in Europe and in one of the top French Universities. They belong to Training and Research Units (UFRs) specializing in Medicine, Pharmaceuticals & the Sciences and Law-Economics-Management. In the light of unprecedented advances in therapy, the School of Cancer Sciences is committed to a modern way for teaching model, which, in particular, is based on visual aids, digital technologies. It is thus engaged in: teaching of theory in the presence of a teacher or by Digital learning, practical teaching a participatory approach towards education with teacher/student design of teaching sessions, collaborative assessments etc. The Institute was founded as a result of the motivation of Professor Gustave Roussy, the father of the concepts of cross-boundary working and multi-disciplinary patient management. For 70 years it has been developing an approach to oncology which remains faithful to its founder’s values: innovation, dynamism, cooperation and benevolence. All of this is built on the three guiding principles: patient care, research and teaching. Gustave Roussy is a source of innovations in treatment and advances in diagnostic techniques. It employs an integrated approach to research, patient care and teaching in order to benefit the patient, and it brings together all the skills which are essential for top quality research in oncology. This encompasses basic research, clinical research and translational research to link the two.