The Institute of Biomedical Research of A Coruña is made up of the research groups of the Hospital, the University and the Primary Care Area of A Coruña, with the aim of creating a stable framework of collaboration, integrating basic and clinical research developed, Making it possible to transfer to society more effectively the scientific advances obtained in the diagnosis, prevention and treatment of diseases.
The scientific structure of INIBIC is developed in six major areas of research. During the process of defining and consolidating these areas, they have worked on the premise of fostering interrelation and collaboration among all the institutions that make up the Institute. Thus, the current composition of the six areas has a marked heterogeneous character, each being integrated by more than one institution, so as to encourage the development of multidisciplinary teams to address the different scientific activities of the Institute.
The INIBIC is made up of scientific professionals from the Galician Health Service - SERGAS, which includes personnel from the health centers both in hospitals and health centers around A Coruña, and from the UDC. Currently, INIBIC has a total of 267 professionals. These professionals make up the 22 groups. Research Areas: • Aging, Inflammation, Regenerative Medicine:
Aging and Inflammation, Rheumatology, Research in Gerontology
• Cardiovascular and Metabolic Diseases:
Advanced Heart Failure and Heart Transplantation, Family Cardiopathies, Ischemic Cardiopathy, Interventional Cardiology and Image and Cardiac Function, Cardiovascular Epidemiology, Primary Care and Nursing, Endocrine, Nutritional and Metabolic Diseases, Cardiac Biomarkers.
• Neuroscience, Oncology, Hematology
Neuroscience and Motor Control, Clinical and Translational Oncology, Research on Von Willebrands Disease.
• Health Technologies, Biomedical Informatics, Telemedicine
Advances in Telemedicine and Health Informatics (ATIS), RNASA – IMEDIR, Artificial Vision and Pattern Recognition (VARPA).
• Genetics, Microbiology, Molecular Medicine
Research in Microbiology, DNA damage and Chromosomes-Toxicogenetics, Xenética of Marine Organisms, Clinical Virology.
• Population Health, Health Care
Clinical Epidemiology and Biostatistics.
• Profesor Novoa Santos Foundation
• Unit of Experimental Surgery
• UICEC (Clinical Research and Clinical Trials Unit)
• Proteomics Platform
• Genomics Platform
• Unit of Clinical Epidemiology and Biostatistics
• Histomorphology Platform Publications:
• Secretome analysis of human articular chondrocytes unravels catabolic effects of nicotine on the joint.
• Apremilast, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis and current skin
involvement: a phase III, randomized, controlled trial (PALACE 3).
• European Mitochondrial Haplogroups Impact on Liver Progressive Fibrosis among HCV and HIV / HCV Coinfected Patients from Northwest Spain.
• Insulin decreases autophagy and leads to cartilage degradation.
• The genome-wide association study identifies a new locus associated with the response to anti-TNF therapy in rheumatoid arthritis.
• 3, 3 , 5-triiodo-L-thyronine Increases In Vitro Chondrogenesis of Mesenchymal Stem Cells From Human Umbilical Cord Stroma Through SRC2.
• Resveratrol lowers synovial hyperplasia, inflammatory markers and oxidative damage in an antigen-induced arthritis model.