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The National Institute of Allergy and Infectious Diseases (NIAID) conducts and supports basic and applied research to better understand, treat, and ultimately prevent infectious, immunologic, and allergic diseases. For more than 60 years, NIAID research has led to new therapies, vaccines, diagnostic tests, and other technologies that have improved the health of millions of people in the United States and around the world. NIAID is one of the 27 Institutes and Centers of the National Institutes of Health (NIH). NIAID conducts and supports basic and applied research to better understand, treat, and ultimately prevent infectious, immunologic, and allergic diseases. For more than 60 years, NIAID research has led to new therapies, vaccines, diagnostic tests, and other technologies that have improved the health of millions of people in the United States and around the world. Our scientists study all aspects of infectious diseases from bench to bedside. With the help of support and administrative staff, they work to find ever better methods of disease prevention, diagnosis, and treatment.
Following is a brief description of the major areas of investigation.
• Acquired Immunodeficiency Syndrome (AIDS). NIAID is responsible for conducting and supporting basic research on the pathogenesis of human immunodeficiency virus (HIV), which causes AIDS; developing new drug therapies; conducting clinical trials of promising experimental drugs for HIV infection and related opportunistic infections and cancers; carrying out epidemiologic studies to assess the impact of HIV on the populations most severely affected by the epidemic; and developing and testing HIV vaccines.
• Asthma and Allergic Diseases. Research on asthma and allergies has revealed much about their underlying mechanisms and contributed to the development of new ways to help affected individuals. NIAID has established a network of asthma, allergic, and immunologic diseases research centers to transfer results from fundamental studies in immunology and clinical studies of allergy to clinical practice. The Institute also supports the National Cooperative Inner-City Asthma Study to define factors that influence the diseases severity and to design and evaluate programs to reduce asthma episodes and deaths among African-American and Hispanic children.
• Vaccine Development. Effective vaccines have contributed enormously to improvements in public health in the United States during the last century. Research conducted and supported by NIAID has led to new or improved vaccines for a variety of serious diseases, including rabies, measles, meningitis, whooping cough, hepatitis A and B, chickenpox, and pneumococcal pneumonia, to name a few.
NIAID supports vaccine evaluation units for the testing of new vaccines in people at a number of U.S. medical centers. Other areas of research include fungal diseases, hospital-associated infections, chronic fatigue syndrome, respiratory diseases, and antiviral and antimicrobial drug development.
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