Alzheimers disease is poised to become the worlds biggest public health challenge. Today, nearly 5.4 million Americas are living with Alzheimers disease—a number that is expected to reach 16 million by 2050. The epidemic will have dire economic consequences, bringing the annual cost of Alzheimers in the United States from $214 billion in 2014 to $1.2 trillion by 2050, while taking an enormous emotional toll on family, friends and caregivers. We have the power to stop this devastating disease in its tracks. By supporting scientists around the globe who are investigating novel drugs to prevent the onset of Alzheimers, slow its progression and effectively treat its symptoms, the Alzheimers Drug Discovery Foundation (ADDF) is working to map a new Alzheimers future for the world.