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Objectives: The aim of this study was to investigate the possible role of TCF7L2 rs 7903146 (C/T) variant on susceptibility of T2DM among Egyptian children and adolescents. Patients and methods: 30 T2DM pediatric patients, 20 obese children and 20 control subjects were enrolled in the study and subjected to: anthropometric measu.. Read More
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Successful Medical Weight Loss in a Community Setting
Background: Research has shown that meal replacement calorie reduction combined with lifestyle change cans more than double the weight loss seen with other diets. However, its widespread acceptance by physicians has been limited, perhaps waiting on evidence that patients are successful in keeping lost weight off. Methods: Obese .. Read More
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Identifying Financial Incentive Designs to Enhance Participation in Weight Loss Programs
Background: Financial incentives are routinely recommended to attract participants to weight loss programs; however there is a paucity of research that uses a systematic approach to determine incentive packages that may be most beneficial in increasing program reach or participation. Methods: The purpose of this study was to det.. Read More
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Background: Underweight, overweight and high blood pressure (BP) are known cardiovascular risk factors in children. The objective of the study was to investigate the relationship between the neck circumference (NC) and mid upper arm circumference (MUAC) with BP in Ellisras rural children age 5-12 years. Methods: All children (n=.. Read More
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Socio-economic Determinants Factors of Overweight and Obesity among Saudi Children
Background: In recent decades obesity has emerged as a serious health issue among adolescents in developed and developing countries. Objective: The aim of this study is to investigate relationship between Socio-economic Status (SES) and obesity among adolescents in both urban and rural areas of Saudi. Methodology: Cross-sectiona.. Read More
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Purpose: To examine possible associations of obesity with mode of transportation to neighborhood facilities, social environment, type of work, and physical activity at neighborhood facilities and at home. Methods: This cross-sectional descriptive survey included a total of 312 respondents aged 18 years or older who attended thre.. Read More
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Background/Aim: The present study investigates the effect of daily green-plant membrane (thylakoid) supplementation for two months on body weight, body composition, metabolic profile and rating of appetite sensations in overweight women on a restricted diet. Methods: 26 women, Body Mass Index (BMI) 27.5 ± 1.9, randomized .. Read More
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The purpose of this study was to determine if a college course in Personal Health and Fitness that includes Fitness Interns (FI) can impact dietary intake, physical fitness and attitudes towards a healthy dietary intake and physical activity among college students. Two different versions of the intervention were delivered as a c.. Read More
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A Short Literature Review on Diabetic Cardiomyopathy in Obese Conditions
Diabetes is associated with most of the risk factors associated to the vital organs like Heart, Kidney, Liver and Brain. Although there is no much evidence to understand the clear mechanism of the Diabetic Cardiomyopathy to have increased Heart Risk, it becomes very important to understand the possibilities or the available hypo.. Read More
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Background: Young women are at high risk of weight gain yet few studies have examined the long-term effectiveness of weight loss programs in this group. This study aimed to investigate the effects of a self-directed internet-based lifestyle program on body weight in young women. Methods: Overweight or obese young women (BMI 33.4.. Read More
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Altered Monoamine Metabolism in High Fat Diet Induced Neuropsychiatric Changes in Rats
Objective: To investigate the role of central and peripheral monoamine metabolism on neuropsychological status in high fat diet induced obese rats. Method: Animals were fed on high fat diet for 12 weeks. Periodically blood was collected to estimate serum Metanephrine (MN) levels. After 11 weeks, behavioural paradigms of depressi.. Read More
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Leptin Gene Mutations in Morbidly Obese and Severely Lean Individuals from Punjab, Pakistan
Obesity has become an epidemic of modern world. Although 6 mutations in the leptin gene have been found to be associated with congenital leptin deficiency, leptin gene polymorphism has not been studied in adult morbidly obese and severely lean individuals. This study involves comparison of obese and lean individuals. In this res.. Read More
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Qualitative and/or Quantitative Drinking Water Recommendations for Pediatric Obesity Treatment
Objective: The qualitative recommendation to ‘drink water instead of caloric beverages’ may facilitate pediatric obesity treatment by lowering total energy intake. The quantitative recommendation to ‘drink enough water to dilute urine’ might further facilitate weight loss by increasing fat oxidation via c.. Read More
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Background: Numerous multi-ingredient weight-loss supplementation products are marketed, whereas the effects of these supplements on weight maintenance have rarely been studied. This study aimed to investigate preliminarily whether a 4-week supplementation of a multi-ingredient weight-loss product (named ‘diet’s BB&r.. Read More
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Objective: Anecdotally, lower leg skin changes in morbidly obese people appear much improved with weight loss following bariatric surgery. The objective of this study was to compare prevalence of lower leg symptoms in obese patients awaiting, and those who have had, bariatric surgery. Methods: An audit was undertaken, utilising .. Read More
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The Role of Overtube-assisted Deep Enteroscopy ERCP in Roux-en-Y Gastric Bypass Patients
Bariatric surgery is the fastest growing medical intervention for obesity performed in theUS and Roux-en-Y Gastric Bypass (RYGB), is considered the "gold standard"comprising more than 60% of these cases. However, patients with surgically alteredanatomy after undergoing RYGB pose serious challenges to the endoscopist wh.. Read More
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Nesfatin – 1: Role as Possible New Anti Obesity Treatment
In this article, we review on the current concepts about Nesfatin-1 as a new anti-obesity treatment and evaluate the existing issues in the context of this knowledge and the available literature. The intent is to enable clinicians to know Nesfatin-1 as a new anti obesity treatment and make rational decisions based on this perspe.. Read More
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Emerging Pharmacotherapies to Fight Obesity and Related Disorders
Obesity is a chronic disease, characterized by an accumulation of excess adipose tissue and associated with an increased risk for cardio-vascular diseases and mortality. Weight loss of a 5-10% prevents or tempers the severity of many obesity-related morbidities. The current therapy of obesity comprises diet, increased physical a.. Read More
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Background and aims: Obesity, a condition born in the rich countries of the West, is rising in the rest of the world. The developing countries are adopting the eating habits and the lifestyle of the rich countries. The purpose of this study was to evaluate, on obese subjects, the effect of a diet therapy with weekly control with.. Read More
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Background: Evidence exists in the adult literature linking obesity to an elevated risk for the development of certain malignancies, and to an increase in treatment-related complications. Little information is available examining this relationship in the obese pediatric oncology population. Methods: We performed a retrospective .. Read More
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