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Hindi Research Article
Short-term Effects of Supplementation with a Multi-ingredient Weight-loss Product on Weight Maintenance and Fat Oxidation in Obese Female with Weight Reduction: Preliminary Results
| Naoki Sakane1*, Kazuhiko Kotani1,2, Kokoro Tsuzaki1, Kaoru Takahashi1,3, Taku Hamada1,4, Narumi Nagai5, Toshio Moritani6, Kahori Egawa7, Makiko Yoshimura8, Yoshinori Kitagawa9 and Hiroshi Shibata7 | |
| 1Division of Preventive Medicine, Clinical Research Institute, National Hospital Organization Kyoto Medical Center, Kyoto, Japan | |
| 2Department of Clinical Laboratory Medicine, Jichi Medical School, Tochigi, Japan | |
| 3Hyogo Preventive Medical Center, Hyogo, Japan | |
| 4Graduate School of Sport and Exercise Science, Osaka University of Health and Sport Sciences, Osaka, Japan | |
| 5Department of Food Science and Nutrition, School of Human Science and Environment, University of Hyogo, Hyogo, Japan | |
| 6Laboratory of Applied Physiology, Graduate School of Human and Environmental Studies, Kyoto University, Kyoto, Japan | |
| 7Institute for Health Care Science, Health Care Science Center, Suntory Wellness Limited, Osaka, Japan | |
| 8Research Institute, Suntory Global Innovation Center Limited, Osaka, Japan | |
| 9Safety Science Institute, Quality Assurance Division, Suntory Business Expert Limited, Osaka, Japan | |
| Corresponding Author : | Naoki Sakane M.D., Ph. D., Division of Preventive Medicine, Clinical Research Institute National Hospital Organization Kyoto Medical Center 1-1 Mukaihata-cho, Fushimi-ku, Kyoto 612-8555, Japan Tel: 075-641-9161 Fax: 075-645-2781 E-mail: nsakane@kyotolan.hosp.go.jp |
| Received September 01, 2014; Accepted October 04, 2014; Published October 11, 2014 | |
| Citation: Sakane N, Kotani K, Tsuzaki K, Takahashi K, Hamada T, et al. (2014) Short-term Effects of Supplementation with a Multi-ingredient Weight-loss Product on Weight Maintenance and Fat Oxidation in Obese Female with Weight Reduction: Preliminary Results. J Obes Weight Loss Ther 4:231. doi:10.4172/2165-7904.1000231 | |
| Copyright: © 2014 Sakane N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | |
Abstract
Background: Numerous multi-ingredient weight-loss supplementation products are marketed, whereas the effects of these supplements on weight maintenance have rarely been studied. This study aimed to investigate preliminarily whether a 4-week supplementation of a multi-ingredient weight-loss product (named ‘diet’s BB’), containing L-carnitine, banaba, caffeine, capsaicin, Nelumbo nucifera leaf extract and sesamin, could contribute to weight maintenance and its related parameters among obese women with weight reduction following a Low-calorie Diet (LCD). Methods: In a prospective, randomized, double-blind intervention design, subjects with ≥5% of weight reduction following LCD were randomized to the group who used the diet’s BB (Group A) or tablet containing six types of vitamins (Group B) for four weeks. Their body weight and related parameters, including Respiratory Quotient (RQ) and fat oxidation, were measured pre- and post-intervention. Results: The changes in body weight and related parameters were not significantly different between the groups. Group A showed significantly reduced RQ and increased fat oxidation more than the Group B. Conclusion: The short-term multi-ingredient weight-loss supplementation product did not yield further weightloss for obese women with weight reduction, while it could potentially lead to favorable changes of fat oxidation levels. The effects of the supplementation on weight traits merit large-scale and long-term investigations.
