Simultaneous Electrochemical Determination of Paracetamol and Folic Acid at Pregabalin Modified Carbon Paste Electrode: A Cyclic Voltammetric Study
Received Date: Mar 07, 2017 / Accepted Date: Mar 07, 2018 / Published Date: Mar 12, 2018
Abstract
In this study, the electrochemical sensor was fabricated for the detection of paracetamol and folic acid by modifying the carbon paste electrode using Pregabalin drug. The fabricated carbon paste electrode was characterized by cyclic voltammetry; the result shows an excellent enhanced elctrocatalytic activity of the modified electrode towards paracetamol and folic acid with combined selectivity and sensitivity. Several kinetic parameters such as area of electrode, nature of electrode process and limit of detection were calculated. The modified carbon paste electrode can successfully use for the determination of paracetamol and folic acid individually and collectively. The limit of detection was found to be 0.093 × 10-5 M, 0.201 × 10-5 M for paracetamol and folic acid respectively. The fabricated electrode can successfully have applied for the detection of paracetamol in pharmaceutical preparations.
Keywords: Paracetamol; Folic acid; Pregabalin; Cyclic voltammetry; Differential pulse voltammetry
Citation: Tanuja SB, Kumara Swamy BE and Vasantakumar Pai K (2018) Simultaneous Electrochemical Determination of Paracetamol and Folic Acid at Pregabalin Modified Carbon Paste Electrode: A Cyclic Voltammetric Study. Ind Chem 4:123. Doi: 10.4172/2469-9764.1000124
Copyright: © 2018 Tanuja SB, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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