Abstract

The CO2-derived calcium carbonate nanoparticles (CaCO3NPs) are promising materials for a variety of industrial applications. Understanding their toxicological profile in biological systems is crucial given that increased synthesis of CaCO3NPs exposes more people and the environment to them. Here, we examine two cell lines and zebrafish in vivo to determine the cytotoxicity of CaCO3NPs made from a CaO slurry (Danio Rerio). Our findings show that CaCO3NPs are safe when used in vitro because they don't kill cells or have any genotoxic effects. Zebrafish exposed to CaCO3NPs also grow and develop normally, supporting the safety and biocompatibility of this nanomaterial.

Keywords: Calcium carbonate; Nanoparticles; Environment toxicity