alexa Wistar Institute

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Wistar Institute

The Wistar Institute was founded in 1892 to conduct anatomical research and training and quickly evolved into a biomedical research facility. Throughout the 20th century, Wistar gained a pioneering reputation in animal model studies and vaccine development. In 1972, Wistar became an NCI-designated cancer center conducting basic research to understand the causes, treatment, and prevention of cancer. The mission of The Wistar Institute is to marshal the talents of outstanding scientists through a highly-enabled culture of biomedical collaboration and innovation, in order to solve some of the world’s most challenging and important problems in the field of cancer, immunology, and infectious diseases, and produce groundbreaking advances in world health. Consistent with a pioneering legacy of leadership in not-for-profit biomedical research and a track record of life-saving contributions in immunology and cell biology, The Wistar Institute aims to pursue novel and courageous research paths to life science discovery, and to accelerate/potentiate the impact of those discoveries by shortening the path from bench to bedside. The Molecular and Cellular Oncogenesis program encompasses the underlying processes of normal and malignant cell growth and differentiation. Members seek to understand the biological impact of specific molecular events associated with tumor formation and progression toward metastatic disease. Several member laboratories are studying large protein complexes and cellular machines, how cellular networks respond to different signaling pathways, and how changes in global patterns of gene expression at the genetic and protein levels – influence normal and disease processes. Wistar, who began his medical practice in 1787, was the author of the first American textbook on anatomy, and succeeded friend Thomas Jefferson as president of the American Philosophical Society. In 1808, Caspar Wistar became chair of the Department of Anatomy at the University of Pennsylvania School of Medicine.   By the late 1880s the collection had grown so large and well used that it began to show signs of wear, a situation compounded by a fire in the University of Pennsylvania hall where the museum was housed. University Provost William Pepper, M.D., began a fundraising campaign to provide refurbishing and a permanent home for the Wistar and Horner collections to assure their continued availability for the study and teaching of medicine.  Isaac Jones Wistar, the great nephew of Caspar Wistar. A prominent Philadelphia lawyer and former Civil War Brigadier General, Isaac Wistar made an initial gift to Provost Pepper’s campaign to save the museum. Determined to create a lasting gift for the serious study of biological research and preserve his great uncle’s teaching collection, Isaac Wistar later funded an endowment and research building for The Wistar Institute of Anatomy and Biology.  The modern era of scientific discovery at The Wistar Institute began under the leadership of Hilary Koprowski, M.D. Beginning in the 1950s, the Institute became a leader in vaccine research. This research was made possible by the discovery of a cell line known as WI-38. Developed by Leonard Hayflick, Ph.D., and Paul S. Moorhead, Ph.D., WI-38 served as the basis for many safe vaccines, including vaccines against rubella and rabies. 

The following is the list of scholars from Wistar Institute who contributed and/or serves as editors for one or more OMICS International journals and conferences

The following is the list of articles by scholars from Wistar Institute that are published in OMICS International journals.

The following is the list of proceedings by scholars from Wistar Institute that are published in OMICS International journals and conferences.