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Heterogeneity and Phenotypic Diversity of Multiple Sistemic Lymphangiomatosis
The lymphatic abnormalities should be considered as entities with local and systemic involvement, of continuous spectrum, being in the majority of cases a diagnosis of exclusion, making the differential diagnosis between entities difficult. Gorham Stout syndrome should be suspected in a patient with rapid and progressive osteol.. Read More
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Artefacts are structures that are not normally present in well prepared smears. Well stained smears are the cornerstone of diagnostic haematology and this requires properly stained smears achieved by adherence to standard operating procedures (SOPs) to ensure reliability of results. Artefacts on smears may baffle the examiner an.. Read More
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Use of Digital Pathology to Drive Revenue to Labs
This paper presents the practical use of digital pathology (DP) as a tool to drive revenue. A regional dermatopathology laboratory developed and patented a digital pathology software system called Clearpath™ featuring a touch-enabled viewer that allows dermatologists to read digital slides remotely and generate pathology r.. Read More
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Squamous Cell Carcinoma in Mature Cystic Teratoma Ovary: A Rare Presentation
Introduction: Mature cystic teratoma also known as dermoid cyst is the most common ovarian tumors accounting for 30%-45% cases. 1. The incidence of Squamous cell carcinoma arising in the mature cystic teratoma is 2%. 2. In this case report we are presenting two cases of squamous cell carcinoma arising in mature cystic teratoma.. Read More
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The Role of p57kip2 Immunohistochemistry in Differentiating Complete from Partial Hydatidiform Mole
Background: The examination of morphological features of gestational products accounts as a core diagnostic process, especially for the distinction of complete hydatidiform mole (CM) from Partial Mole (PM) cases. Nevertheless, subjective evaluation of the traditional histopathological criteria might occur with substantial intero.. Read More
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Purpose: The incidence of papillary thyroid cancer (PTC) with concomitant Hashimoto’s thyroiditis (HT) is increasing. Interleukin-10 (IL-10) is a cytokine previously reported to be elevated in this condition. Evidence from multiple human malignancies showed IL-10 participated in tumor immunity and exhibited therapeutic pot.. Read More
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Background: Capillary hemangiomas of the skin and soft tissue are a common entity, while capillary hemangiomas of the central nervous system are an extremely rare pathology. There are less than 20 published cases of intradural lesions involving the cauda equina. Case presentation: Herein, we describe a young patient with a capi.. Read More
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Chelation and Gadolinium: How Effective is it?
Gadolinium-Based Contrast Agents (GBCA) are intravenous drugs used in diagnostic imaging procedures to enhance the quality of magnetic resonance imaging (MRI) or magnetic resonance angiography (MRA). Recent FDA alerts concerning potential side effects increased patient and medical concerns. We checked if gadolinium remains in th.. Read More
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Mucinous Adenocarcinoma of Gall Bladder: A Rare Case Report
Gall bladder (GB) carcinoma is the fifth most common malignancy of gastrointestinal tract. Mucinous carcinoma (MC) of gall bladder is a very rare variant of gall bladder carcinoma. To the best of our knowledge, only 20 cases of mucinous carcinomas have been reported till date. We report a case of 42-year-old female patient who p.. Read More
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Immunohistochemical Expression of Androgen and Estrogen Receptors
Urothelial carcinoma is the most common malignancy affecting the urinary tract. It is at least three times more common in males than females suggesting the role of sex hormones in initiation and progression of bladder cancer. The purpose of this study is to detect the immunohistochemical expression of androgen receptors (AR.. Read More
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Significance of Expression of Cancer Stem Cell Markers CD133
Pancreatic adenocarcinoma of ductal origin (PDAC) is considered one of the most aggressive malignancies and also one of the most chief causes of deaths related to cancer. It has a very poor prognosis and high recurrence rate. We investigated the expression of CSC markers (CD133 and nestin) in different grades of pancreatic intra.. Read More
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A Superficial Leiomyosarcoma of the Ankle: Case Report
Leiomyosarcoma of the ankle is a rare occurrence. It typically manifests in the 4th to 6th decades of life with no definite gender predilection. Frequently, it is misdiagnosed clinically as a benign entity due to a seemingly indolent disease course. Herein, we describe an 81-year old gentleman who presented to his primary care p.. Read More
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Renal Primitive Neuroectodermal Tumor in a Child with Brain Metastasis: A Case Report
Primitive neuroectodermal tumor (PNET) is a malignant small round cell tumor that typically arises from bone or soft tissue in adolescents and young adults. Renal PNET is extraordinarily rare and exhibits highly aggressive biological behavior with poor prognosis. It generally occurs in young adults and only a few pediatric cases.. Read More
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Objective: Hypertension has been increased dramatically nowadays; this might be due to the modern life which increases the pressure on individuals. So, the study aims to assess the knowledge of risk factors of hypertension among the medical sciences students in International University of Africa (IUA). In the meantime, the relat.. Read More
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Removal of Polyacrylamide Hydrogel Injected in Different Layers for Breast Augmentation
Background: The complications of polyacrylamide hydrogel (PAAG) injected for breast augmentation have captured the attention of the physicians and patients. More and more patients are seeking for the removal of it. In this article, we analyzed the effectiveness of the removal of PAAG injected for breast augmentation by using an .. Read More
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Geophagy in Children: A Rare Cause of Bowel Obstruction
Geophagy is an eating disorder defined by an irresistible urge to ingest soil or clay. This cosmopolitan practice has always challenged the medical world. The aim of our work is to discuss a rare case of intestinal obstruction due to geophagy and to illustrate the role of imaging in the diagnosis and management of this condition.. Read More
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Ethno pharmacological relevance: People in Nigeria and all over the world, use this plant preparations, for various therapeutic purposes, in folklore medicine. The aim of the study is to obtain the sub chronic nephrotoxic and hepatotoxic information on this plant. Aim of study: Obtain nephrotoxic and hepatotoxic information rega.. Read More
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Background: Cryptococcosis affects 10-30% of patients with acquired immunodeficiency syndrome (AIDS) resulting in significant morbidity and mortality. The primary sites of cryptococcal disease are the lung and central nervous system with bone marrow involvement being rare.Case presentation: This case report describes a human imm.. Read More
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Macropephaly-Cutis Marmorata: Case Report and Review of Literature
Macrocephaly - capillary malformation (M-MC) is a rare genetic disorder initially described in 1997. It is associated with a spectrum of abnormalities including macrocephaly, cerebral and body asymmetry, cutaneous vascular malformations and digital anomalies. It is one of several overgrowth syndromes known as the hypertrophic sp.. Read More
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Toxicological Studies of Aqueous Extract of Adenia cissampeloides in Clarias batrachus Fish
The study was aimed at investigating effects of aqueous stem extract of Adenia cissampeloides on selected liver function biomarkers of Clarias batrachus fish. We determined lethal concentration (LC 50) of the extract to the fish; assayed aspartate aminotran sferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (.. Read More
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