Axillary Masse, is it an Ectopic Mammary Gland?
ISSN: 2572-4118
Breast Cancer: Current Research
Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on Medical, Pharma, Engineering, Science, Technology and Business
  • Case Report   
  • Breast Can Curr Res, Vol 1(2): 108
  • DOI: 10.4172/2572-4118.1000108

Axillary Masse, is it an Ectopic Mammary Gland?

Ferjaoui Mohamed Aymen1*, Youssef Atef1, Gharrad Majed1, Boujelbene Nadia2, Ben Amara Fethi1 and Rziga Hedi1
1Department B of Gynecologic and Breast Surgery, Tunis Maternity Center, Tunis Medical School, Tunisia
2Department of Pathology, Salah Azaiez Institute, Tunis Medical School, Tunisia
*Corresponding Author: Ferjaoui Mohamed Aymen, Department B of Gynecologic and Breast Surgery, Tunis Maternity Center, Tunis Medical School, Tunisia, Tel: 0033619420762, Email: [email protected]

Received Date: Apr 29, 2016 / Accepted Date: May 16, 2016 / Published Date: May 30, 2016


Ectopic breast tissue or super numerary mammary gland is a congenital condition characterized by the development of mammary tissue along the embryonic milk line. This condition Occurs in 0.4-6% of the general population. The most common site of development of super numerary mammary gland is the axillar region. Axillary ectopic breast tissue may provide a diagnostic challenge, as other benign and malignant lesions occur in this area. We report a case of 18 years-old girl presenting an axillary masse considered firstly as an ectopic mammary gland. Ultrasound aspect and axillary MRI correct the diagnosis and lead to provide specific management of this tumor.

Keywords: Ectopic breast tissue; Nervous tumor; Axillary masse


The axillar region can be the location of much benign or malignant tumor. The most frequent are lymphadenopathy (lymph node reaction after infectious, inflammatory or malignant diseases). Ectopic breast tissue, the most common breast congenital disease, can be considered as a differential diagnosis of axillary masse [1]. Many other rare tumors must be included. Clinical assessment of axillary region can be unhelpful and ultrasound or MRI imaging can be required to establish the right diagnosis [2].

The Case Report

The reported case is about an 18 years-old girl without any medical history. She presented progressively a right axillary masse. Clinical examination showed an axillary delimited soft masse, movable relative to deep plane. An axillary ectopic breast tissue was suspected (Figures 1 and 2). Breast ultrasound examination and mammogram were normal. Axillary ultrasound showed a homogenous delimited solid tumor measuring 6 cm (Figure 3). This examination wasn't helpful to determine the origin of this tumor. An axillary MRI was performed. It showed a multi lobular encapsulated solid tumor, measuring 6 cm. This tumor was closely near to the humeral head and to nervous structure (Figures 4 and 5). We decided to proceed to a surgical biopsy through an axillary incision. The histological examination showed an axillary shwannoma, a peripheral benign nervous tumor (Figures 6 and 7). The patient underwent a tumoral excision in the department of plastic and hand surgery. The after-surgery follow-up was without complications.


Figure 1: Right axillary soft tumor, movable relative to deep plane.


Figure 2: Right axillary soft tumor, movable relative to deep plane.


Figure 3: Ultrasound examination showed a homogenius and delimited tumor measuring 6 cm.


Figure 4: MRI imaging (frontal and transverse incidence) showed a multi lobular solid and encapsulated tumor located deeply in the axillar region and near to humeral head and nervous structure.


Figure 5: MRI imaging (frontal and transverse incidence) showed a multi lobular solid and encapsulated tumor located deeply in the axillar region and near to humeral head and nervous structure.


Figure 6: Spindle cell neoplasm with areas of hypocellularity and areas of dense cellularity.


Figure 7: Tumors cells are positive for S100.


Ectopic breast tissue is a rare congenital condition occurring in 0.4 to 6% of general population. It is the most common breast congenital abnormality. This entity is divided to two histologic subgroups: supernumerary breast and aberrant breast tissue.

The difference between those subtypes is that the first one consists on an organized ductal system communicating with its overlying skin, whereas the latter is characterized by an unorganized secretory system which has no communication to the overlying skin [3,4]. Ectopic breast tissue is more frequently localized in the axilla [5] but other localizations have been reported in parasternal, subclavicular, submammary, vulvar and anal regions [4-6].

The ectopic breast tissue can be complicated as a normally lactated breast tissue especially by benign and malignant tumors such as carcinoma, intraductal papilloma, fibroadenoma and fibrocystic disease [7,8].

In our case, we had a diagnostic challenge related to the unusual clinical presentation of the described tumor (consistency, clinical characteristic), a ultrasound examination and MRI were needed showing an atypical and unusual aspect of a multi lobular encapsulated solid tumor, measuring 6 cm. histological examination was the only way to establish the diagnosis, it was an axillary shwannoma.

This is a benign tumor of schwann cells, produces a wellcircumscribed, slowly growing lesion. It is the most common benign peripheral nerve lesion. Nerve tumors comprise less than 5% of all upper extremity tumors. Schwannoma usually occurs in the fore arm and hand, but cervical and axillary tumors have been reported [9,10].

Concerning axillary masses, the most common diagnosis is palpable lymph node (secondary to infectious, inflammatory or malignant malformation, lipoma, cysts, hidradentitis suppurativa and ectopic breast tissue. Schwanomma should be included in the differential diagnosis of axillary masses because it has also been reported in the axilla. In addition, schwanoma often is confused with other soft tissue masses, and inadvertent nerve biopsy may lead to permanent disability. Seventeen percent of peripheral nerve trauma is due to iatrogenic injury [11]. Injury to the spinal accessory nerve has been documented after  [12] nerve injury after axillary lymph node biopsy has not been reported previously. In our case surgical biopsy was performed and fortunately no complications or nerve injury were seen. Preoperative magnetic resonance imaging may help delineate peripheral nerve sheath tumors in the axilla if the diagnosis is suspected. In addition, clear visualization of the mass is necessary before excision to prevent significant nerve injury.

This case is important to study because of difficulties and challenge to diagnose axillary masse. Many types of tumor occur in this region. In a Department of gynecologic and breast surgery, the mostly frequent axillary masse is related to breast disease such lymph node involvement in case of breast cancer or ectopic mammary gland. MRI is a good tool to have an idea about the origin and the management of axillary masses.

When shwannoma is suspected, a specialist intervention, investigation and management are required. Biopsy is not allowed because of the risk of iatrogenic nerve injuries. Nervous tumor especially shwannoma are to keep in mind when we are confronted to deal with axillary tumor.

Conflict of Interest Statement

We declare that we have no conflict of interest.


Citation: Aymen FA, Atef Y, Majed G, Nadia B, Fethi BA, et al. (2016) Axillary Masse, is it an Ectopic Mammary Gland?. Breast Can Curr Res 1: 108. Doi: 10.4172/2572-4118.1000108

Copyright: ©2016 Aymen FM et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Select your language of interest to view the total content in your interested language

Post Your Comment Citation
Share This Article
Article Usage
  • Total views: 12562
  • [From(publication date): 6-2016 - Jul 30, 2021]
  • Breakdown by view type
  • HTML page views: 12366
  • PDF downloads: 196
Share This Article