Abstract

Calypso is an internal electromagnetic motion monitoring technology to localize and track tumors in a real-time and direct way to allow accurate treatment. It has been nearly two decades since its invention and the first Calypsobased stereotactic liver radiotherapy in China was successfully implemented and evaluated in our institution. To thoroughly understand this technology, it is more beneficial to comprehensively investigate the development of Calypso all over the world besides China, which may facilitate the motion management-based radiotherapy methodologies and guide the way for its future applications. In this mini review, a brief description of thorough retrospect, current status analysis and prospect was illustrated. It is shown that Calypso is gradually spreading out from developed countries to developing countries, and it is used for more carcinoma types. It is hoped that this mini review can inspire more Calypso application cases and provide a firm faith in its bright future.

Keywords: Calypso; Radiotherapy; Internal electromagnetic motion monitoring, Beacon transponder; Motion management