alexa Assay of the Level of Calcium, Magnesium and Inorganic
ISSN: 2161-0681

Journal of Clinical & Experimental Pathology
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Research Article

Assay of the Level of Calcium, Magnesium and Inorganic Phosphorus in HIV Infected Patients in Owerri, Southeast Nigeria

Obum-Nnadi CN1, Onyenwe Nathaniel2*, Mbata TI3, Udeji GN4 and Okoro JC5

1Department of Microbiology, Imo State University, Owerri, Nigeria

2Department of Pharmaceutical Microbiology, Faculty of Pharmacy, University of Ibadan, Nigeria

3Department of Microbiology, Federal Polytechnic Nekede, Owerri, Nigeria

4Department of Public Health, Ministry of Health Owerri, Imo State, Nigeria

5Department of Paediatrics, College of Medicine, Imo State University Teaching Hospital Owerri, Nigeria

*Corresponding Author:
Onyenwe Nathaniel
Department of Pharmaceutical Microbiology
Faculty of Pharmacy, University of Ibadan, Nigeria
Tel: 08037797813
E-mail: [email protected]

Received Date: December 12, 2012; Accepted Date: January 22, 2013; Published Date: January 24, 2013

Citation: Obum-Nnadi CN, Nathaniel O, Mbata TI, Udeji GN, Okoro JC (2013) Assay of the Level of Calcium, Magnesium and Inorganic Phosphorus in HIV Infected Patients in Owerri, Southeast Nigeria. J Clin Exp Pathol 3:134. doi: 10.4172/2161-0681.1000134

Copyright: © 2013 Obum-Nnadi CN, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

HIV is a retrovirus, but differs from other retroviruses such as Human T Lymphotrophic Viruses (HTLV) 1 and 2, is transmitted sexually and pre-natally. A total of eighty HIV/AIDS patients attending heart to heart in a Federal Medical center were assayed for the presence of Calcium, Magnesium and inorganic Phosphates which are among trace elements found in the human body, in relation to their CD4 cell counts. The mean (mMol/l) value and Standard Deviation of Calcium, Magnesium and Inorganic phosphates on the HIV infected male patients were investigated to be 1.96 ± 0.49(Ca),1.01± 0.80(Mg), and 1.03 ± 0.09(P) respectively, while the mean (mMol/l) value and Standard Deviation (SD) were 1.96 ± 0.49 (Ca), 0.99 ± 1.70 (Mg), and 1.07 ± 0.25 respectively. The infection rate was high on the female between the age range of 21-30 and 31-40 years with a prevalence rate of 33.5% (27) and 15.0% (12) respectively. Spectrophotometric assay using flow cytometer counter reported that the CD4 cell count of each individual infected with HIV is not dependent or have positive correlation or significant effects at (p>0.05) on the level of concentrations of Calcium, magnesium and inorganic phosphates in the plasma, when compared to the controls and the normal estimate value for trace elements in human plasma. Based on the assay and statistical significance, the CD4 cell count of each individual patient infected with HIV or not, was assumed to be dependent on the anatomical composition and physiological state of their body, dietrary and environmental factors as well as educational exposure of the individual.

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