Can a Diagnosis be Ruled Out Based on One Cortisol Result? A Case Report on Delayed Diagnosis of HypopituitarismJames P*, Gupta P and Patel P
Department of Chemical Pathology and Metabolic Medicine, University Hospitals Leicester NHS Trust, UK
- *Corresponding Author:
- James P
Department of Chemical Pathology
and Metabolic Medicine
Level 4 Sandringham Building
Leicester Royal Infirmary, Leicester
LE1 5WW, UK
Email: jam[email protected]
Received date: May 30, 2015 Accepted date: July 07, 2015 Published date: July 10, 2015
Citation:James P, Gupta P, Patel P (2015) Can a Diagnosis be Ruled Out Based on One Cortisol Result? A Case Report on Delayed Diagnosis of Hypopituitarism. J Clin Exp Pathol 5: 237. doi:0.4172/2161-0681.1000237
Copyright: ©2015 James P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
There are numerous potential causes for hyponatraemia including hypovolaemia; oedema; syndrome of inappropriate ADH secretion; and acute episodes of Addison’s disease (hypopituitarism and adrenal insufficiency) . Hyponatraemia can have serious consequences for patients and there are many ways to investigate the cause. Here we present a case of an elderly patient presenting with hyponatraemia and highlight the limitations of the standard dose (250 mcg) short synacthen test (SST) for the investigation of adrenal insufficiency as a potential cause of hyponatraemia.