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Can a Diagnosis be Ruled Out Based on One Cortisol Result? A Case Report on Delayed Diagnosis of Hypopituitarism | OMICS International| Abstract
ISSN: 2161-0681

Journal of Clinical & Experimental Pathology
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  • Case Report   
  • J Clin Exp Pathol 2015, Vol 5(4): 237
  • DOI: 10.4172/2161-0681.1000237

Can a Diagnosis be Ruled Out Based on One Cortisol Result? A Case Report on Delayed Diagnosis of Hypopituitarism

James P*, Gupta P and Patel P
Department of Chemical Pathology and Metabolic Medicine, University Hospitals Leicester NHS Trust, UK
*Corresponding Author : James P, Department of Chemical Pathology and Metabolic Medicine, Level 4 Sandringham Building, Leicester Royal Infirmary, Leicester, LE1 5WW, UK, Tel: 01162586550, Fax: 01162586550, Email: [email protected]

Received Date: May 30, 2015 / Accepted Date: Jul 07, 2015 / Published Date: Jul 10, 2015

Abstract

There are numerous potential causes for hyponatraemia including hypovolaemia; oedema; syndrome of inappropriate ADH secretion; and acute episodes of Addison’s disease (hypopituitarism and adrenal insufficiency) [1]. Hyponatraemia can have serious consequences for patients and there are many ways to investigate the cause. Here we present a case of an elderly patient presenting with hyponatraemia and highlight the limitations of the standard dose (250 mcg) short synacthen test (SST) for the investigation of adrenal insufficiency as a potential cause of hyponatraemia.

Citation: James P, Gupta P, Patel P (2015) Can a Diagnosis be Ruled Out Based on One Cortisol Result? A Case Report on Delayed Diagnosis of Hypopituitarism. J Clin Exp Pathol 5:237. Doi: 10.4172/2161-0681.1000237

Copyright: © 2015 James P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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