Abstract

Objective: We have studied to verify indication of the combined therapy with intraperitoneal lavage and intraduodenal infusion of Korean rhubarb extract and oxil mixture for severe acute pancreatitis and reduce rate of operation for acute pancreatitis.
Methods: We have studied palliative treatment of severe pancreatitis with intraperitoneal lavage and intraduodenal infusion of Korean rhubarb extract and oxil mixture instead of operative therapy.
Results: According to efficacy of our combined therapy, 83 cases (92.2%) had treated perfectly, but 7 cases (7.8%) had operation therapies due to non-efficacy on our combined therapy. Average duration of hospitalization and recovery of working ability were 21.6 ± 13.6 and 34.6 ± 10.5 respectively in study group, which were shorter than 49.8 ± 19.0, 66.5 ± 17.9 in control group.
Conclusion: We applied intraperitoneal lavage and intraduodenal infusion of Korean rhubarb extract and oxil mixture for severe acute pancreatitis that needed surgical therapy in the past. Thus, the incubus of therapy was induced so recovery after operation, hospital stay and recovery of working ability was reduced than those of surgical therapy for severe acute pancreatitis.

Keywords: Intraperitoneal lavage; Korean rhubarb extract; Oxil mixture; Severe acute pancreatitis; Double-drain; Intraduodenal infusion; Kocher’s maneuver; Pancreatic capsulotomy; Pancreatic ojejunostomy; Pancreatic fistula