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ISSN: 2161-0681

Journal of Clinical & Experimental Pathology
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  • Research Article   
  • J Clin Exp Pathol 2016, Vol 6(2): 271
  • DOI: 10.4172/2161-0681.1000271

Comparison of Quality of Life after Mandibular Resection: A Cohort Study of Patients in the Same Institution

Anyanechi CE1*, Edet ES2 and Saheeb BD3
1Department of Dental Surgery, Oral and Maxillofacial Unit, University of Calabar, University of Calabar Teaching Hospital, Calabar, Nigeria
2Department of Community Medicine, University of Calabar Teaching Hospital, Calabar, Nigeria
3Department of Oral and Maxillofacial Surgery, University of Benin, University of Benin Teaching Hospital, Nigeria
*Corresponding Author : Anyanechi CE, Department of Dental Surgery, University of Calabar Teaching Hospital, Eastern Highway, Calabar, Nigeria, Tel: +2348100257825, Email: [email protected]

Received Date: Feb 04, 2016 / Accepted Date: Apr 22, 2016 / Published Date: Apr 25, 2016

Abstract

Objective: The surgical treatment of benign locally invasive lesions of the mandible can have deleterious effects on a patient’s quality of life (QOL). To evaluate and compare the QOL in two cohort groups of patients who underwent mandibular resection for benign locally invasive lesions of the mandible. Methods: This was a seven year prospective study using the modified University of Washington Quality of life (UW-QOL) Questionnaire, version 4. The two cohorts studied were those that were rehabilitated, and those not rehabilitated. The questionnaire was administered to the patients at 18 months after marginal mandibular and segmental mandibular resections respectively. Statistical analysis was performed using EPI INFO 7 software package and level of significance was set at p<0.05. Results: This showed that 71/87 subjects who had resections responded; 34 marginal mandibular, and 37 segmental mandibular were studied. The socio-demographic variables presented no statistically significant relationship regardless of the status of rehabilitation. Most patients without rehabilitation had a lower QOL score for functional daily activities like chewing, speech and psychological effects of low mood and anxiety compared with the rehabilitated group; and that socio-economic class of the patients was the best predictor of better QOL. Conclusion: The major concerns of patients who have undergone mandibular resection were chewing ability, speech, appearance, anxiety and low mood, and these concerns were expressed more in the non-rehabilitated. The trends and determinant of QOL observed should be used to decide targeted support in order to assist the patients overcome their deformities and disabilities.

Keywords: Mandibular resection; Quality of life; Cohort study; Outcome assessment

Citation: Anyanechi CE, Edet ES, Saheeb BD (2016) Comparison of Quality of Life after Mandibular Resection: A Cohort Study of Patients in the Same Institution. J Clin Exp Pathol 6:271. Doi: 10.4172/2161-0681.1000271

Copyright: © 2016 Anyanechi CE, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Review summary

  1. David R
    Posted on Jul 14 2016 at 11:49 pm
    The topic of study and the results interpreted are worth publishing. It is a worthwhile study for general clinicians and oral surgeons. The authors may include details regarding the time of interview as well as the procedures followed for better readability.
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