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Depression and Quality of Life in Patients with Inflammatory Bowel Diseases | OMICS International| Abstract
ISSN: 2161-069X

Journal of Gastrointestinal & Digestive System
Open Access

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  • Research Article   
  • J Gastro intest DigSyst,
  • DOI: 10.4172/2161-069X.1000679

Depression and Quality of Life in Patients with Inflammatory Bowel Diseases

Jacqueline Sundstrom* and Sol-Britt Lonne Rahm
Center for Clinical Research, Sweden
*Corresponding Author : Jacqueline Sundstrom, Center for Clinical Research, Sweden, Email: [email protected]

Received Date: Mar 15, 2022 / Published Date: Apr 12, 2022


This cross-sectional study was carried out to find prevalence and possible relation between decreased quality of life and depression among patients with inflammatory bowel disease.

Aims: Due to possible common biological pathways between inflammation in IBD and depression and due to the high burden of depression on both patient and health care institution, it is important to identify and initiate treatment to improve quality of life, disease outcome and reversed events associated with depression.

Methods: 41 patients with either Crohn’s disease or ulcerative colitis participated in a questionnaire based interview. Beck’s depression inventory was used for depression assessment and quality of life. Peripheral blood was collected for analyzing inflammatory and anemia markers. Data was then used for statistical analysis.

Results: Most patients were clinically free of depression. However, there was a strong correlation between number of exacerbations and depression in patients with Ulcerative Colitis, there was a negative correlation between serum leukocytes and depression, and the use of Mesalazine had a protective effect.

Conclusion: Inflammation in the gut may provoke depressive phenotype and vice versa. This may be caused by biological, social and psychological factors. Depression may also cause decreased quality of life, why it is necessary to identify these symptoms early and thereby reduce the risk of decreased quality of life.

Keywords: Depression; Inflammation; IBD; Quality of life

Citation: Sundström J, Rahm SL (2022) Depression and Quality of Life in Patients with Inflammatory Bowel Diseases. J Gastrointest Dig Syst 12:679. Doi: 10.4172/2161-069X.1000679

Copyright: © 2022 Sundström J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.