Abstract

Pediatric laboratory diagnostics is rapidly evolving with innovations in genetic testing for critically ill children and comprehensive
newborn screening for conditions like Severe Combined Immunodeficiency. Clinical Laboratory Utilization Committees effectively
optimize diagnostic test ordering in pediatric oncology. Challenges persist in diagnosing pediatric invasive fungal infections, Congenital
Adrenal Hyperplasia, and rare diseases, requiring advanced molecular methods and collaborative networks. Insights into acute
poisoning, new oral anticoagulants, and cancer biology, such as miR-203a-3p in rhabdomyosarcoma, continue to advance pediatric
care.