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Hindi Gastroprotective effect of Sargassum wightii fractions on Indomethacin induced gastric ulcer in Wistar Albino Rats
*Corresponding Author:Received Date: Dec 05, 2023 / Published Date: Feb 03, 2025
Citation: Suganyadevi P, Manokiruthika V, Varshini R, Hariprasath L, Muthusami S (2025) Gastroprotective Effect of Sargassum wightii Fractions on Indomethacin Induced Gastric Ulcer in Wistar Albino Rats. J Gastrointest Dig Syst 15: 846.
Copyright: © 2025 Suganyadevi P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Abstract
Seaweeds or marine macroalgae have been reported to have various biological activities including antioxidant, antiviral, antibacterial, antiprotozoal, antifungal, anti-inflammatory, antitumor, antidiabetic, antineoplastic, anti cholinesterase, anti-tyrosinase anticoagulant, hypolipidemia and hypercholesterolemia. Sargassum wightii is brown seaweed which is used for our research, the fractions were isolated, showed a good anti-ulcer activity in wistar rat model system. The results showed that 250 mg/kg of the seaweed extract a good anti-ulcer activity as compared with the standard drug (20 mg/kg Omeprazole). From this study Sargassum wightii can be used for the treatment of Gastric ulcer.
