Glyphosate Intoxication Presenting with Bilateral Pneumothoraces and Boerhaave’s Syndrome: A Case Report | OMICS International| Abstract
ISSN: 2476-2067

Toxicology: Open Access
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  • Case Report   
  • Toxicol Open Access,
  • DOI: 10.4172/2476-2067.1000154

Glyphosate Intoxication Presenting with Bilateral Pneumothoraces and Boerhaave?s Syndrome: A Case Report

Beyers BD1*, Landman FR1, Jacobs SJ2, Swartbooi A2, Beyers A3 and Rodriguez GLN4
1Department of Medicine, Univesity of RSA, Kimberley, South Africa
2Department of Radiology, University of Cape Town, Kimberley, South Africa
3Department of Health Science, University of Cape Town, Kimberley, South Africa
4Department of Health Sciences, University of the Free State, Kimberley, South Africa
*Corresponding Author : Beyers BD, Community Service Medical Officer: Internal Medicine Robert Mangaliso Sobukwe Hospital, Kimberley, South Africa, Tel: +27 (0) 79695 8693, Email: [email protected]

Received Date: Feb 11, 2021 / Accepted Date: Feb 25, 2021 / Published Date: Mar 01, 2021


In this case report we present a young, healthy male, presenting to hospital 5 days after ingesting Roundup®, a glyphosate-containing herbicide. His main complaints included haematemesis, pleuritic chest pain and dyspnoea. Initial assessment revealed a Left Pneumothorax (PTX) for which an intercostal drain (ICD) was inserted. On further evaluation he had Acute Kidney Injury (AKI), toxic hepatitis and developed a right sided PTX on the third day of admission. Pneumomediastinum was identified on follow-up chest x-ray (CXR). These findings, in conjunction with his presenting complaints and the clinical finding of Hamman’s crunch on auscultation, a diagnosis of Boerhaave’s syndrome was postulated, which was confirmed on contrast enhanced Computed Tomography (CT) of the chest with swallow. A brief overview of glyphosate toxokinetics and Boerhaave’s syndrome is provided.

Keywords: Glyphosate; Boerhaave’s syndrome; pneumomediastinum; Oesophageal perforation

Citation: Beyers BD, Landman FR, Jacobs SJ, Beyers A, Rodriguez GLN, et al (2021) Glyphosate Intoxication Presenting with Bilateral Pneumothoraces and Boerhaave’s Syndrome: A Case Report. Toxicol:Open Access 7:154. Doi: 10.4172/2476-2067.1000154

Copyright: © 2021 Beyers BD, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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