ISSN: 2161-0681

Journal of Clinical & Experimental Pathology
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  • Research Article   
  • J Clin Exp Pathol 2015, Vol 5(2): 217
  • DOI: 10.4172/2161-0681.1000217

Intra and Post Circumcision Bleeding in Nigerian Neonates: Correlation with Hemostatic Parameters

Eyitayo Emmanuel Fakunle1, Kapoona Iwara-Ibiang Eteng2, Wuraola Adebola Shokunbi3 and Clyde Wilson1*
1Department of Pathology, King Edward VII Memorial Hospital, Bermuda
2National Health Insurance Scheme, Abuja, Nigeria
3Department of Hematology, University College Hospital, Ibadan, Oyo-State, Nigeria
*Corresponding Author : Clyde Wilson, Department of Pathology, King Edward VII Memorial Hospital, Paget, Bermuda, Tel: (441) 239 1418, Fax: 1441 236 9200, Email: clyde.wilson@bhb.bm

Received Date: Dec 09, 2014 / Accepted Date: Mar 11, 2015 / Published Date: Mar 15, 2015

Abstract

Circumcision is one of the oldest operations known. In Nigeria there is dearth of knowledge about the incidence of post-circumcision bleeding. Only one out of every seven males in the world is circumcised, however circumcision is the rule rather than the exception within all Nigerian ethnic groups and religions. This study investigated the relationship between some hemostatic parameters, family history and bleeding associated with circumcision of male infants in Ibadan, South West Nigeria. Materials and methods: The study design involved a population of 244 male infants drawn from University College Hospital and Oluyoro Catholic Hospital, in Ibadan, Nigeria. Pre-circumcision PT and aPTT, factor VIIIc level, Platelet Count, incidence of Intra and post-operative bleeding were determined. Results: None of the infants had a family history of bleeding disorder or thrombocytopenia. Six of the full term neonates (2.5%) had prolonged PT while only 2 of the subjects (0.8%) had prolonged aPTT. The factor VIIIc level was between 31-49% in 16.1%, while 1.6% of the neonates had levels between 20-26%. Intra-operatively, 28.9% (manual method, Gomco Clamp) and 4.9% (plastibell) had moderately severe bleeding while excessive postcircumcision bleeding was found in 2.8% and 6.8% for manual methods and plastibell respectively. Conclusion: There was a positive correlation between pre-circumcision aPTT and the degree of post circumcision bleeding. A relationship would have been expected to exist between post-circumcision bleeding and factor VIIIc but this was not found to be significant in this study. Activated Partial Thromboplastin Time would probably be sufficient as a screening hemostatic test for the detection of neonates that may be at risk of bleeding post-operatively.

Keywords: Bleeding; Circumcision; Hemostatic parameters

Citation: Fakunle EE, Eteng KI, Shokunbi WA, Wilson C (2015) Intra and Post Circumcision Bleeding in Nigerian Neonates: Correlation with Hemostatic Parameters. J Clin Exp Pathol 5:217. Doi: 10.4172/2161-0681.1000217

Copyright: © 2015 Fakunle EE, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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