Investigation of Water-Soluble Silver Ion and Silver Nanoparticles in Wound Dressing using ICP-MS
Received Date: Feb 15, 2019 / Accepted Date: Mar 11, 2019 / Published Date: Mar 18, 2019
Due to its anti-microbial properties, silver has been used in wound treatment for many decades. In some cases, the wound is covered a week or longer with a foam dressing that contains silver as an anti-microbial agent. Although more expensive, silver laden dressings have been found to be more effective at reducing the microbial load, thereby allowing more rapid wound healing. However, the exact mechanism of silver’s anti-microbial property is still unclear and the form of the silver that is most effective is unknown. Even though many manufacturers have begun to incorporate silver nanoparticles in wound dressings, there currently exists no U.S. regulation as to which form is to be used, nor at what concentration. This paper explores the water-soluble form of silver in several commercially available wound dressings both through size characterization of the ionic and nanoparticle forms and measurement of each form’s silver concentrations by ICP-MS. The method as a whole represents the beginning of a larger project to investigate the most effective form and optimum concentration of silver for wound dressing inclusion to promote maximum healing.
Keywords: Silver ion; Silver nanoparticle; Wound dressing; ICP-MS
Citation: Vonderheide AP, Chatterjee R, Walsh M, Savu A (2019) Investigation of Water-Soluble Silver Ion and Silver Nanoparticles in Wound Dressing using ICP-MS. J Anal Bioanal Tech 10:414. Doi: 10.4172/2155-9872.1000414
Copyright: © 2019 Vonderheide AP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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