Abstract

This compilation reviews critical aspects of cellular metabolism, highlighting its dynamic role in health and disease. It explores metabolic reprogramming, mitochondrial function, and specific nutrient metabolisms, including fatty acids and amino acids. The papers delve into dysregulation in cancer, obesity, and metabolic syndrome, emphasizing the impact of nutrient sensing and the gut microbiome. Furthermore, the interplay between metabolism and epigenetics, alongside the profound effects of exercise on muscle metabolism, is discussed. Together, these articles underscore metabolism’s central role in physiological adaptation, disease pathology, and therapeutic potential across diverse biological systems.