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microRNAs in Neurodegeneration: Current Findings and Potential Impacts | OMICS International| Abstract
ISSN: 2161-0460

Journal of Alzheimers Disease & Parkinsonism
Open Access

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  • Review Article   
  • J Alzheimers Dis Parkinsonism 2018, Vol 8(1): 420
  • DOI: 10.4172/2161-0460.1000420

microRNAs in Neurodegeneration: Current Findings and Potential Impacts

Salil Sharma and Hui-Chen Lu*
Department of Psychological and Brain Sciences, The Linda and Jack Gill Center for Bimolecular Sciences, Indiana University, Bloomington, IN 47405, USA
*Corresponding Author : Hui-Chen Lu, Department of Psychological and Brain Sciences, The Linda and Jack Gill Center for Bimolecular Sciences, Indiana University, Bloomington, IN 47405, USA, Tel: 812-856-4998, Fax: 812-856-7187, Email: [email protected]

Received Date: Jan 02, 2018 / Accepted Date: Jan 16, 2018 / Published Date: Jan 23, 2018

Abstract

Significant advancements have been made in unraveling and understanding the non-coding elements of the human genome. New insights into the structure and function of noncoding RNAs have emerged. Their relevance in the context of both physiological cellular homeostasis and human diseases is getting appreciated. As a result, exploration of noncoding RNAs, in particular microRNAs (miRs), as therapeutic agents or targets of therapeutic strategies is under way. This review summarizes and discusses in depth the current literature on the role of miRs in neurodegenerative diseases.

Keywords: microRNAs; MiRs; Dementia; Neurodegeneration

Citation: Sharma S, Lu HC (2018) microRNAs in Neurodegeneration: Current Findings and Potential Impacts. J Alzheimers Dis Parkinsonism 8: 420. Doi: 10.4172/2161-0460.1000420

Copyright: ©2018 Sharma S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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