Neuroprotective Effects of Selective Serotonin Reuptake Inhibitors | OMICS International| Abstract

Journal of Molecular Immunology
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  • Research   
  • J Mol Immunol 2018, Vol 3(1): 118

Neuroprotective Effects of Selective Serotonin Reuptake Inhibitors

James Allen Wilcox*
Department of Psychiatry, College of Medicine Tucson, University of Arizona, USA
*Corresponding Author : James Allen Wilcox, Department of Psychiatry, College of Medicine Tucson, 3601 S 6th Ave Tucson Arizona, University of Arizona, USA, Email: [email protected]

Received Date: Jan 09, 2018 / Accepted Date: Jan 23, 2018 / Published Date: Jan 30, 2018


Serotonin reuptake inhibitors (SSRIs) have been suggested to have a neuroprotective effect. This claim is is largely clinical and not previously supported by evidence based data. This area of neuroscience has not been well studied at the cellular level. This study offers a three part laboratory examination of the effect of SSRIs on glia cells. The investigation found that serotonin reuptake inhibitors had a detectable protective effect on glia when tested under various classic methods. The examination of cell morphology, use of vital dyes, cell death and growth rates were consistent with a neuroprotective class effect. The data suggest that serotonin reuptake inhibitors are, in fact neuroprotective at normal physiologic dosages.

Keywords: Neuroprotective; Serotonin; Glia neuron

Citation: Wilcox JA (2018) Neuroprotective Effects of Selective Serotonin Reuptake Inhibitors. J Mol Immunol 3: 118.

Copyright: © 2018 Wilcox JA. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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