Non-HLA Antibodies in Renal Transplantation, Where Do We Stand?
Received Date: Nov 25, 2018 / Accepted Date: Dec 18, 2018 / Published Date: Dec 26, 2018
Abstract
Objective: This review discusses current findings in the subject and addresses the clinical relevance of Non-HLA antibodies.
Methods: This traditional narrative review used PubMed and Medline searches for English language reports on Non HLA abs during last 20 years. The search included the key words: non-human leukocyte; antibodies; kidney; transplantation.
Results: 65 related articles and review were found.
Conclusion: Non-HLA immunity is associated with poor graft survival, rejection and chronic graft loss. Moreover, they could be used as biomarkers of ongoing immune response and as predictors of graft failure.
Keywords: Non-human leukocyte; Antibodies; Kidney; Transplantation
Citation: El Hennawy HM (2018) Non-HLA Antibodies in Renal Transplantation, Where Do We Stand?. J Clin Exp Transplant 3: 125. Doi: 10.4172/2475-7640.1000125
Copyright: © 2018 El Hennawy HM. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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