Percutaneous Ethanol Injection Treatment, Novel Solution for the Challenge of Recurrent Thyroid Pathology: A ReviewParisha Bhatia1, Tatyana E. Fontenot2, Koji Tsumagari1, Emad Kandil1,2*
- *Corresponding Author:
- Emad Kandil
Department of Otolaryngology
Tulane Otolaryngology-Head & Neck Surgery 1430 Tulane Avenue
SL 59, New Orleans, LA 70112, USA
E-mail: [email protected]
Received date: March 22, 2014; Accepted date: April 26, 2014; Published date: April 28, 2014
Citation: Bhatia P, Fontenot TE, Tsumagari K, Kandil E (2014) Percutaneous Ethanol Injection Treatment, Novel Solution for the Challenge of Recurrent Thyroid Pathology: A Review. J Clin Exp Pathol 4:172. doi:10.4172/2161-0681.1000172
Copyright: © 2014 Bhatia P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Introduction: Thyroid nodules are among the most common endocrine complaints in the United States. With increasing incidence of differentiated thyroid carcinoma there has been a widespread interest in development of minimally invasive treatments such as percutaneous ethanol injection (PEI) to manage thyroid pathology. In our review of published literatures, we discuss the application of ethanol injection for treatment of benign thyroid nodules and its efficacy in treating locally recurrent papillary thyroid carcinoma.
Evolving treatment roles of PEI: PEI has been most successful at treating recurrent cystic nodules. In hyperfunctioning nodules, PEI is indicated for patients who are poor surgical and radioiodine therapy candidates. Initial trials of PEI in metastatic lymph nodes in papillary thyroid carcinoma have yielded promising therapeutic results with only minor side effects. PEI does not remove the option of future radio-frequency ablation or surgery which may become necessary in some cases.
Conclusion: In our opinion, percutaneous ethanol injection proves to be a superior treatment modality for benign thyroid nodules showing markedly higher success in cystic nodules. Its safety and efficacy in treating recurrent papillary thyroid carcinoma is significant.