The Neurologist: Clinical & Therapeutics Journal
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
  • Review Article   
  • Neurol Clin Therapeut J 2018, Vol 2(1): 1

Omental Transplantation against NMO and MS: A Method to Decrease or Prevent Relapses

Rafael H*
Neurosurgeon, Academia peruana de Cirugía, , Lima, Peru
*Corresponding Author : Rafael H, Neurosurgeon, Academia peruana de cirugía, Bélgica 411-BIS, 03303 Mexico City, Mexico, Tel: +5255-5532 9101, Email: hrtumi@yahoo.com

Received Date: Jan 04, 2018 / Accepted Date: Jan 23, 2018 / Published Date: Jan 30, 2018

Abstract

To date, we do not know the etiological agents of Neuromyelitis Optica (NMO) and Multiple Sclerosis (MS) that trigger the production of specific antibodies (autoimmune reaction) in the bloodstream, against aquaporin-4 (AQP4) and myelin oligodendrocyte glycoprotein (MOG) antigens located in the astrocytes and oligodendrocytes, respectively. Agents that also cause immunological abnormalities, which damage the intima of the arteries and the blood brain barrier (BBB). Thus, AQP4 and MOG antibodies, as well as cytokines and activated leukocytes cross the injured BBB to cause inflammation, demyelination and degeneration. The clinical course in both diseases is generally characterized by periods of relapses and remissions. For these reasons, based on previous neurosurgical experiences, I believe that an omental transplantation on the optic chiasma and anteromedial temporal lobes can decrease or prevent relapses. Because the omentum produces revascularization and provides stem cells to the hypothalamus and surrounding zones.

Keywords: NMO; MS; Hyperactivity of the Hypothalamic-pituitary-adrenal (HPA) axis; Chronic stress; AQP4 antigen; MOG antigen

Citation: Rafael H (2018) Omental Transplantation against NMO and MS: A Method to Decrease or Prevent Relapses. Neurol Clin Therapeut J 2: 102.

Copyright: © 2018 Rafael H. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Top