Production of Novel Antiprotozoal and Anthelminthic Compounds from Marine Surface Associated Bacteria
Received Date: Dec 26, 2018 / Accepted Date: Jan 28, 2019 / Published Date: Feb 05, 2019
Parasitic infections are the most prevalent in humans in developing countries and one third of the world population are infected by intestinal parasites. In addition, it affects millions of heads of livestock throughout the world. Global infections and widespread drug resistances exhibited by both protozoa and helminthes which have great challenge to present medicine. New medicine or bioactive may be talented solution of this problem. Combinatorial biosynthesis is one of the approaches for protecting parasitic infection but bioactive from natural origin provides diversity and structural complexity of the compounds with densely packed functional groups allowing maximum selectivity and interaction to the target. Currently the majority of antibiotics used in clinical practice are natural product origin. Living marine surfaces provide environment rich epibiotic microorganisms (e.g., bacteria) that produce bioactive compounds. By improving the culturability and using upgrade techniques it is possible to overcome the challenge of bioactive production. Microorganisms are currently accepted as the best renewable source of bioactive and marine living surface have great potential of producing novel bioactive compounds useful for further drug development. This review evaluate that marine surface associated bacteria are great source for production of novel antiprotozoal and anthelminthic compounds.
Keywords: Global infection; Bioactive; Antiprotozoal; Anthelminthic compounds; Microorganisms
Citation: Sala Uddin GM, Nejum MR, Islam MR, Islam MM (2019) Production of Novel Antiprotozoal and Anthelminthic Compounds from Marine Surface Associated Bacteria. J Marine Sci Res Dev 9: 266. Doi: 10.4172/2155-9910.1000266
Copyright: © 2019 Sala Uddin GM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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