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Prothymosin Alpha (ProTand#945;) and Thymosin Beta (Tand#946;): Conserved Immune-related Genes from Teleost to Mammals | OMICS International| Abstract

Journal of Molecular Immunology
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  • Short Communication   
  • J Mol Immunol 2016, Vol 1(1): 102

Prothymosin Alpha (ProTα) and Thymosin Beta (Tβ): Conserved Immune-related Genes from Teleost to Mammals

Zhu Y1, Shen J2 and Xiao Z2*
1Department of Gastroenterology, , the Third Affiliated Hospital of Soochow University, Changzho, China
2Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, Sichuan, PR China
*Corresponding Author : Xiao Z, Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, Sichuan, PR China, Tel: 86-830-3162291, Email: [email protected]

Received Date: Jul 08, 2016 / Accepted Date: Jul 08, 2016 / Published Date: Jul 27, 2016

Abstract

Prothymosin alpha (ProTα) and thymosin beta (Tβ), members of the thymosin family, consist of a series of highly conserved peptides capable of stimulating immune responses in different species. Our recently published report discussed an issue of the conserved roles of ProTα b and Tβ-like (Tβ-l) in common carp (Cyprinus carpio L), which suggested that the highly-conserved carp ProTα b and Tβ-l can ultimately enhance immune response during viral infection and modulate the development of T lymphocytes in Teleost. These results enthusiastically pilled more evidences of evolutionary conservation of thymosins.

Keywords: Prothymosin alpha; Thymosin beta; Teleost; Immune responses

Citation: Zhu Y, Shen J and Xiao Z (2016) Prothymosin Alpha (ProTα) and Thymosin Beta (Tβ): Conserved Immune-related Genes from Teleost to Mammals. J Mol Immunol 1:102.

Copyright: © 2016 Zhu Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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