Why is Cardiac Morbidity and Mortality Greater Around Christmas, New Year’s, Monday Mornings and in the Morning Hours: Potential Roles of Unrecognized Ionized Hypomagnesemia and Release of Ceramides?

Burton M Altura^1,2,3,4,5*, Joshua Burack⁶, RF Tranbaugh⁶, Z Zisbrod⁶, JN Cunningham⁶, Nilank C Shah^1,5, Gatha J Shah¹, Lawrence M Resnick⁷ and Bella T Altura^1,3,4,5

¹Department of Physiology And Pharmacology, State University of New York, Downstate Medical Center, Brooklyn, New York, USA

²Department of Medicine, State University of New York, Downstate Medical Center, Brooklyn, New York, USA

³Center for Cardiovascular and Muscle Research, State University of New York, Downstate Medical Center, Brooklyn, New York, USA

⁴School of Graduate Studies in Molecular and Cellular Science, State University of New York, Downstate Medical Center, Brooklyn, New York, USA

⁵Bio-Defense Systems, Inc, , Rockville Center, New York, USA

⁶Department of Surgery, State University of New York, Downstate Medical Center, Brooklyn, New York, USA

⁷Department of Medicine, Cornell University School of Medicine, , New York, USA