Abstract

Maintenance of high energy availability in blood is associated with functional disorders and vascular diseases. Much longer endurance of high energy availability, of insulin resistance and of the associated overall subclinical inflammation may increase DNA replications and constitute the main factor in the development of malignancy. Current research is mainly oriented to solve the malignancy risk by “Personalized Medicine”. This approach moves away from a one size fits to the treatment and care of patients with a particular condition. The medical model of personalized Medicine separates people into different groups. Medical decisions, practices, interventions and/or products being tailored to the individual patient based on their predicted response or risk of disease. The “tailoring” is mainly obtained by studying the genome. In face of a malignancy, the study of genome might predict the best intervention. We do not discourage this cumbersome and expensive way of creating a genetically individualized treatment for everyone. We made studies on conditioned intake to solve other problems. This conditioned feeding is now prevalent but is associated with overall subclinical inflammation. In tissues involved by inflammation develops an accelerated turnover of immune cells and of parenchymal cells. The increase in cellular replications increases DNA duplications and DNA mutations as in malignant tumors. Prevention of malignancy requires cessation of conditioned intake and maintenance of lower energy availability. Suppression of conditioned intake appears more effective in malignancy prevention and fruitful for general health than studying genomic differences in any individuals after malignancy arousal.

Keywords: Blood Glucose; Diabetes; Insulin resistance; Overweight; Fattening; Energy balance; Energy intake; Limit in energy intake; Hunger; Meal onset; Energy availability; Malignant diseases; Bowel disorders; Malnutrition