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Salivary Duct Carcinoma in Minor Salivary Glands: Report of Two Cases with Different Clinical Behavior | OMICS International| Abstract
ISSN: 2161-0681

Journal of Clinical & Experimental Pathology
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  • Case Report   
  • J Clin Exp Pathol 2014, Vol 4(2): 164
  • DOI: 10.4172/2161-0681.1000164

Salivary Duct Carcinoma in Minor Salivary Glands: Report of Two Cases with Different Clinical Behavior

Rogério O. Gondak1*, Fernanda V. Mariano2, Fabio A. Alves3, Oslei P. Almeida2 and Márcio A. Lopes4
1Department of Pathology, Federal University of Santa Catarina, Brazil
2Division of Oral Pathology, Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, Brazil
3Department of Stomatology, A. C. Camargo Cancer Hospital, Brazil
4Department of Oral Diagnosis, University of Campinas, Brazil
*Corresponding Author : Rogério O. Gondak, Department of Pathology, Federal University of Santa Catarina, Delfino Conti Street S/n, Florianópolis, SC. CEP 88040-900, Brazil, Tel: 554837213482, Email: [email protected]

Received Date: Jan 16, 2014 / Accepted Date: Mar 14, 2014 / Published Date: Mar 19, 2014

Abstract

Salivary duct carcinoma (SDC) is a malignant epithelial tumor extremely rare in minor salivary glands. This manuscript describes two cases of SDC of the minor salivary glands with different clinical behaviors. The first patient was an 80-year-old man who had SDC (T1N0M0) in the upper buccal fornix and the second patient was a 64-yearold man with a tumor (T2N2cM0) in the soft palate. Patients were treated with radical surgical resection and none patient underwent postoperative radiotherapy or chemotherapy. Histopathologically, the lesions showed proliferation of ductal cells with varying degrees of nuclear pleomorphism arranged in solid and cribriform structures and prominent comedonecrosis. The patient with SDC in the soft palate developed metastases and died shortly after diagnosis while the patient with SDC in upper alveolar ridge is alive without disease for over 6 years of follow-up. Although SDC is aggressive, anatomical site and precocious diagnosis are relevant factors for better prognosis.

Keywords: Salivary duct carcinoma; Minor salivary gland; Alveolar ridge; Soft palate

Citation: Gondak RO, Mariano FV, Alves FA, Almeida OP, Lopes MA (2014) Salivary Duct Carcinoma in Minor Salivary Glands: Report of Two Cases with Different Clinical Behavior. J Clin Exp Pathol 4:164. Doi: 10.4172/2161-0681.1000164

Copyright: © 2014 Gondak RO, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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