ISSN: 2161-0681

Journal of Clinical & Experimental Pathology
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  • Research Article   
  • J Clin Exp Pathol 2017, Vol 7(6): 331
  • DOI: 10.4172/2161-0681.1000331

Smoking Effects on Blood Antioxidants Level: Lactate Dehydrogenase, Catalase, Superoxide Dismutase and Glutathione Peroxidase in University Students

Qussay N. Raddam1*, Moafaq M. Zeidan2, Mostafa A. Abdulrahman3 and Nahla K.Asaad3
1Department of Biology, College of Education, Al-Iraqia University, Iraq
2Department of Biology, College of Science, Tikrit University, Iraq
3Department of Biology, College of Education, Samarra University, Iraq
*Corresponding Author : Qussay N. Raddam, Department of Biology, College of Education, Al-Iraqia University, Iraq, Email: qussai74@yahoo.com

Received Date: Nov 13, 2017 / Accepted Date: Dec 12, 2017 / Published Date: Dec 17, 2017

Abstract

Smoking has been involved as a significant risk factor for series and establishment of diseases. The aim of our study to investigate smoking effects induced oxidative damage. We have chosen male students of Al-Iraqia University and Tikrit University, aged 20-23 years. In our study we measured activity of Lactate Dehydrogenase (LDH), Catalase (CAT), Superoxide Dismutase (SOD), and Glutathione Peroxidase (GXp). Our results showing that the level of LDH in smokers were higher than nonsmokers, and the levels of CAT was higher in group of nonsmokers ,while SOD and GXp were higher significantly in non-smokers when comparison with smoker students. Also we study the height, body weight, body mass index (BMI), and some of blood parameters red blood cells (RBCs), White blood cells (WBCs), and hemoglobin (Hb). Results showing significant differences between smokers and nonsmokers, all of these parameters were lower in smokers. These results perhaps indicate that smoker students have oxidative stress and shortness in antioxidants defense system.

Keywords: Lactate dehydrogenase; Catalase; Superoxide dismutase; Glutathione peroxidase; Blood

Citation: Raddam QN, Moafaq MZ, Mostafa AA, Nahla KA (2017) Smoking Effects on Blood Antioxidants Level: Lactate Dehydrogenase, Catalase, Superoxide Dismutase and Glutathione Peroxidase in University Students. J Clin Exp Pathol 7: 331. Doi: 10.4172/2161-0681.1000331

Copyright: ©2017 Raddam QN, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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