Soft Tissue Rosai-Dorfman Disease with Unusual Histopathologic Features: A Case Report
Received Date: Dec 04, 2017 / Accepted Date: Dec 11, 2017 / Published Date: Dec 14, 2017
Rosai-Dorfman disease is a rare proliferative histiocytic disorder of unknown etiology. It is a unique disorder of the lymph nodes but extranodal sites such as bone, skin, central nervous system, upper respiratory tract and soft tissue may be affected. Rosai-Dorfman disease is presented with massive, symmetrical cervical lymphadenopathy, fever, leucocytosis, elevated sedimantation rate and hipergamaglobulinemia. Soft tissue presentation can masquerading as a sarcoma. 61 year old women referred with painless left thigh mass to our hospital. After a excisional biopsy histopathologic results showed sheets of histiocytes with emperipolesis admixed in a mixture of inflammatuary cells including plasma cells and lymphocytes. Additionally, we observed pseudovascular spaces and asteroid bodies in large histiocytes. After surgery the patient has been followed up for 1 year postoperatively, without any sign of reccurence. We herein report a case of soft tissue Rosai-Dorfman disease wich presented with unusual features such as pseudovascular spaces and asteroid bodies in histiocytes.
Keywords: Rosai-Dorfman disease; Soft tissue; Pseudovascular spaces; Asteroid bodies
Citation: Canten T, Ferit TO, Alpaslan U (2017) Soft Tissue Rosai-Dorfman Disease with Unusual Histopathologic Features: A Case Report. J Clin Exp Pathol 7: 330. Doi: 10.4172/2161-0681.1000330
Copyright: ©2017 Canten T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Select your language of interest to view the total content in your interested language
Share This Article
Open Access Journals
- Total views: 1760
- [From(publication date): 0-2017 - Aug 06, 2021]
- Breakdown by view type
- HTML page views: 1612
- PDF downloads: 148