Soft Tissue Rosai-Dorfman Disease with Unusual Histopathologic Features: A Case Report
Received Date: Dec 04, 2017 / Accepted Date: Dec 11, 2017 / Published Date: Dec 14, 2017
Rosai-Dorfman disease is a rare proliferative histiocytic disorder of unknown etiology. It is a unique disorder of the lymph nodes but extranodal sites such as bone, skin, central nervous system, upper respiratory tract and soft tissue may be affected. Rosai-Dorfman disease is presented with massive, symmetrical cervical lymphadenopathy, fever, leucocytosis, elevated sedimantation rate and hipergamaglobulinemia. Soft tissue presentation can masquerading as a sarcoma. 61 year old women referred with painless left thigh mass to our hospital. After a excisional biopsy histopathologic results showed sheets of histiocytes with emperipolesis admixed in a mixture of inflammatuary cells including plasma cells and lymphocytes. Additionally, we observed pseudovascular spaces and asteroid bodies in large histiocytes. After surgery the patient has been followed up for 1 year postoperatively, without any sign of reccurence. We herein report a case of soft tissue Rosai-Dorfman disease wich presented with unusual features such as pseudovascular spaces and asteroid bodies in histiocytes.
Keywords: Rosai-Dorfman disease; Soft tissue; Pseudovascular spaces; Asteroid bodies
Citation: Canten T, Ferit TO, Alpaslan U (2017) Soft Tissue Rosai-Dorfman Disease with Unusual Histopathologic Features: A Case Report. J Clin Exp Pathol 7: 330. Doi: 10.4172/2161-0681.1000330
Copyright: ©2017 Canten T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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